Sezary Syndrome Clinical Trials

A listing of Sezary Syndrome medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 21 clinical trials
BI-1808 as a Single Agent and With Pembrolizumab in Treatment of Advanced Malignancies(Keynote-D20)

iRECIST can be applied for efficacy assessment) and subjects with cutaneous T-cell lymphoma (CTCL), specifically Sézary Syndrome (SS) and mycosis fungoides (MF). The study will consist of 2 phases

  • 38 views
  • 07 Oct, 2022
  • 5 locations
IPH4102 Alone or in Combination With Chemotherapy in Patients With Advanced T Cell Lymphoma (TELLOMAK)

This is an open label, multi-cohort, and multi-center phase II study, which evaluates the clinical activity and safety of IPH4102 in Sezary Syndrome and Mycosis fungoides as single agent.

ct scan
fungal infection
skin biopsy
flow cytometry
large cell lymphoma
  • 61 views
  • 11 Jul, 2022
  • 46 locations
Mogamulizumab + Low-Dose Total Skin Electron Beam Tx in Mycosis Fungoides & Sézary Syndrome

The purpose of this study is to determine the efficacy of the combination of LD-TSEBT and mogamulizumab in patients with MF and SS. And to evaluate the secondary measures of clinical benefit of the combination therapy and to evaluate the safety and tolerability of the combination in patients with MF …

imiquimod
bone marrow procedure
metastatic tumor
interferon
retinoids
  • 19 views
  • 25 Apr, 2022
  • 1 location
Pembrolizumab in Combination With Gemcitabine in People With Advanced Mycosis Fungoides or Sézary Syndrome

The purpose of this study is to find out whether the combination of pembrolizumab and gemcitabine is an effective treatment for mycosis fungoides and Sézary syndrome.

mycosis fungoides and sezary syndrome
metastatic tumor
chemotherapy regimen
pet scans
prednisone
  • 0 views
  • 07 Jul, 2022
  • 7 locations
Dosing of Brentuximab Vedotin for Mycosis Fungoides, Sezary Syndrome Patients

The purpose of this study is to test any good and bad effects of the study drug called brentuximab vedotin at a lower dose than is FDA-approved.

mycosis fungoides and sezary syndrome
brentuximab
immunomodulator
prednisone
sezary syndrome
  • 115 views
  • 05 Mar, 2022
  • 8 locations
Mogamulizumab and Extracorporeal Photopheresis for the Treatment of Sezary Syndrome or Mycosis Fungoides

This phase Ib/II trial investigates the side effects of mogamulizumab and extracorporeal photopheresis and to see how well they work in treating patients with Sezary syndrome or mycosis

systemic disease
extracorporeal photopheresis
skin biopsy
chemotherapy regimen
interferon
  • 0 views
  • 10 Jul, 2022
  • 1 location
Naloxone Hydrochloride Study for Relief of Pruritus in Patients With MF or SS Forms of CTCL

pruritus in patients with the mycosis fungoides (MF) or Sézary syndrome (SS) Forms of Cutaneous T-cell Lymphoma (CTCL). This study will also determine if there is systemic absorption of the drug in a

hysterectomy
skin biopsy
naloxone hydrochloride
lymphoma
sezary syndrome
  • 0 views
  • 26 Mar, 2022
  • 19 locations
A Phase I Study With an Expansion Cohort of Duvelisib and Nivolumab in Mycosis Fungoides (MF) and Sezary Syndrome (SS)

Sezary syndrome. Duvelisib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's

  • 7 views
  • 24 Oct, 2022
  • 5 locations
Pembrolizumab in Treating Patients With Stage IB-IV Mycosis Fungoides

This phase II trial studies how well pembrolizumab works in treating patients with stage IB-IV mycosis fungoides. Antibodies, such as pembrolizumab, may interfere with the ability of cancer cells to grow and spread.

metastatic tumor
systemic therapy
erythropoietin
pet scans
serum pregnancy test
  • 9 views
  • 10 Apr, 2022
  • 1 location
Extracorporeal Photopheresis and Mogamulizumab for the Treatment of Erythrodermic Cutaneous T Cell Lymphoma

This phase II trial studies the effect of extracorporeal photopheresis (ECP) and mogamulizumab in treating patients with erythrodermic cutaneous T cell lymphoma (CTCL), a type of skin lymphoma. CTCL is a rare type of cancer that begins in the white blood cells called T cells. Erythrodermic is a widespread red …

bone marrow procedure
extracorporeal photopheresis
skin biopsy
monoclonal antibodies
metastases
  • 0 views
  • 07 Oct, 2022
  • 1 location