Substance Abuse Clinical Trials

A listing of Substance Abuse medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 279 clinical trials
Collaboration Leading to Addiction Treatment and Recovery From Other Stresses (CLARO)

Collaboration Leading to Addiction Treatment and Recovery from Other Stresses (CLARO) is a five-year project that tests whether delivering care using a collaborative model helps patients with both opioid use disorders and mental health disorders.

depression
depressed mood
opioid
  • 37 views
  • 07 Oct, 2022
  • 3 locations
Sequential and Comparative Evaluation of Pain Treatment Effectiveness Response (SCEPTER)

VETERANS ONLY. Chronic low back pain (cLBP) is common. Most Americans will have at least one episode of low back pain in their lifetimes. Approximately 50% of all US Veterans have chronic pain, and CLBP is the most common type of pain in this population. This study will use a …

  • 0 views
  • 04 Oct, 2022
  • 4 locations
Kentucky Communities and Researchers Engaging to Halt the Opioid Epidemic (CARE2HOPE)

This study will test the effects of an intervention to reduce substance use and related harms among people leaving rural jails or otherwise involved in the criminal justice system. This study will compare people in a health linkage intervention with people who will get overdose (OD) education. Everyone will take …

hepatitis c
substance use
Accepts healthy volunteers
hepatitis
opioid
  • 17 views
  • 04 Oct, 2022
  • 1 location
Effects of Cannabis on Prescription Drug Abuse Liability and Analgesia

The purpose of this research is to assess the impact of cannabis on the analgesic and abuse-liability effects of a sub-threshold dose of a commonly used analgesic.

opioid use
Accepts healthy volunteers
oxycodone
opioid
narcotic use
  • 33 views
  • 18 Oct, 2022
  • 1 location
Neuromodulation and Cognitive Training for Substance Use Disorders

The relapsing nature of substance use disorder is a major obstacle to successful treatment. About 70% of those entering treatment will relapse within one year. To improve treatment outcome, new

  • 6 views
  • 04 Oct, 2022
  • 1 location
Non-invasive Brain Stimulation of the Prefrontal Cortex in Substance Use Disorders (NIBSSUD)

Every year, alcohol causes 3 million deaths worldwide. Even though a lot of treatments already exist, many of them are characterized by a high percentage of drop-out or relapse. Transcranial direct current stimulation (tDCS), a NIBS, is receiving increased attention as a possible new addiction treatment. However, little consensus exists …

  • 0 views
  • 18 Oct, 2022
Eye Movement Desensitization and Reprocessing as a Treatment for Substance Use Disorders

Substance Use Disorders (SUD) are often comorbid with psychological trauma, however, the complex interaction between the two is not yet fully understood. Most addiction-specialized professionals

addiction
substance use
  • 0 views
  • 04 Oct, 2022
  • 1 location
Post-Hospital Intervention for Veterans With Comorbid Bipolar and Substance Use Disorders

This trial aims to evaluate the effectiveness of a novel intervention for Veterans with co-occurring bipolar and substance use disorders following a psychiatric hospitalization. Half of the

mood disorder
substance use
  • 0 views
  • 07 Oct, 2022
  • 1 location
Reducing Stigma Toward Mental Illness and Substance Use Issues in Primary Health Care in Chile: A Cluster Randomized Control Trial.

This research project aims to determine the effectiveness of a comprehensive anti-stigma intervention in reducing stigmatizing attitudes and behaviours among Primary Health Care (PHC) providers toward individuals with mental illness and/or substance use issues (MISUI) in the Chilean context, using Centros de de Salud Familiar (CESFAMs) as the point of …

  • 0 views
  • 23 Oct, 2022
Impact of Repeatedly-Administered THC-cannabis on Experimental Pain and Abuse Liability in Humans

disorders and fatal overdoses. Identifying non-opioid medications for the management of chronic pain with minimal abuse liability is a public health necessity, and cannabinoids are a promising drug class

opioid
hyperalgesia
chronic pain
Accepts healthy volunteers
  • 0 views
  • 07 Oct, 2022
  • 1 location