Substance Abuse Clinical Trials

A listing of Substance Abuse medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 326 clinical trials
An Evaluation of Virtual Psychiatric Transition of Care Offered in Behavioral Health (VPTC)

The primary objective is to evaluate the effectiveness of a post inpatient discharge virtual psychiatric care team compared to standard care, to reduce 30-day all cause non-elective acute care utilization (Emergency Department (ED), observation, and inpatient encounters).

Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 2 locations
Effect of Intravenous S-ketamine on Opioid Consumption

Female patients with an American Society of Anesthesia (ASA) physical status I-II, scheduled for elective breast cancer surgery will be included in the study. Subjects will be randomly assigned to one of three groups: the placebo group, the low-dose S-ketamine group, and the high-dose S-ketamine group. The primary outcome is …

  • 7 views
  • 04 Oct, 2022
  • 1 location
Kentucky Women's Justice Community Opioid Innovation Network (W-JCOIN)

This trial will test the effectiveness of delivering medication for opioid use disorder (MOUD) pre-treatment via telehealth, alone and with peer navigation, to increase MOUD initiation and maintenance in the community following jail release. This trial will focus on incarcerated women in 6 experimental and 3 control sites in Kentucky. …

Accepts healthy volunteers
  • 48 views
  • 04 Oct, 2022
  • 8 locations
NIDA-CTN-0100: Optimizing Retention, Duration and Discontinuation Strategies for Opioid Use Disorder Pharmacotherapy (RDD)

This is a two phase study investigating combinations of pharmacological and behavioral interventions to optimize the treatment of Opioid Use Disorder (OUD). The Retention Phase will assess strategies for improving retention on buprenorphine (BUP) and extended-release injectable naltrexone (XR-NTX). The Discontinuation Phase will assess which approaches are most likely to …

  • 76 views
  • 14 Oct, 2022
  • 18 locations
Effects of E-cigarette Flavors on Youth TCORS 2.0

This study is an examination of the influence of sweet and cooling flavors on the appeal and abuse potential of nicotine-containing e-cigarettes among susceptible youth.

  • 0 views
  • 06 Apr, 2023
  • 1 location
Amerlioration of Opioid Withdrawal-Induced Anxiety and Craving With Heterodyned Whole-Body Vibration (HWBV)

through withdrawal of OUD and being treated at local substance abuse clinics. The study visits will include screening, baseline, Weeks 1, 2, 3, and 4, with both safety and efficacy assessments.

  • 0 views
  • 29 Oct, 2022
  • 1 location
Regional Partnership for Pregnant Women at Risk of Substance Misuse and Their Newborns

; they may receive services as usual, or enhanced services. Enhanced services include evidence based interventions and case management to support referrals to substance abuse treatment, and to teach

Accepts healthy volunteers
  • 1 views
  • 03 Apr, 2023
  • 1 location
The Effects of Cold Adaptation on Skin Blood Flow, Hand Function, and Comfort in Healthy Adults

elicits an adaptive habituation response that is characterized by blunted skin vasoconstriction and thus may be an effective strategy to improve peripheral perfusion, reduce thermal discomfort, and

Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 1 location
Potential Effects of Electronic Nicotine Delivery System Flavor Regulations on African American Menthol Smokers (RVA Flavors)

, toxicant exposure, and abuse liability among African American menthol smokers.

Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 1 location
Clinical Trials of Multivalent Opioid Vaccine Components

oxycodone [Oxy(Gly)4-sKLH], one of the most commonly abused prescription opioids. The vaccination approach to treating substance use disorders relies on the ability of the vaccine to produce antibodies that

Accepts healthy volunteers
  • 31 views
  • 04 Oct, 2022