Substance Abuse Clinical Trials

A listing of Substance Abuse medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 298 clinical trials
An Evaluation of Virtual Psychiatric Transition of Care Offered in Behavioral Health (VPTC)

The primary objective is to evaluate the effectiveness of a post inpatient discharge virtual psychiatric care team compared to standard care, to reduce 30-day all cause non-elective acute care utilization (Emergency Department (ED), observation, and inpatient encounters).

Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 2 locations
Effect of Intravenous S-ketamine on Opioid Consumption

Female patients with an American Society of Anesthesia (ASA) physical status I-II, scheduled for elective breast cancer surgery will be included in the study. Subjects will be randomly assigned to one of three groups: the placebo group, the low-dose S-ketamine group, and the high-dose S-ketamine group. The primary outcome is …

  • 7 views
  • 04 Oct, 2022
  • 1 location
Kentucky Women's Justice Community Opioid Innovation Network (W-JCOIN)

This trial will test the effectiveness of delivering medication for opioid use disorder (MOUD) pre-treatment via telehealth, alone and with peer navigation, to increase MOUD initiation and maintenance in the community following jail release. This trial will focus on incarcerated women in 6 experimental and 3 control sites in Kentucky. …

Accepts healthy volunteers
  • 48 views
  • 04 Oct, 2022
  • 8 locations
NIDA-CTN-0100: Optimizing Retention, Duration and Discontinuation Strategies for Opioid Use Disorder Pharmacotherapy (RDD)

This is a two phase study investigating combinations of pharmacological and behavioral interventions to optimize the treatment of Opioid Use Disorder (OUD). The Retention Phase will assess strategies for improving retention on buprenorphine (BUP) and extended-release injectable naltrexone (XR-NTX). The Discontinuation Phase will assess which approaches are most likely to …

  • 76 views
  • 14 Oct, 2022
  • 18 locations
Amerlioration of Opioid Withdrawal-Induced Anxiety and Craving With Heterodyned Whole-Body Vibration (HWBV)

through withdrawal of OUD and being treated at local substance abuse clinics. The study visits will include screening, baseline, Weeks 1, 2, 3, and 4, with both safety and efficacy assessments.

  • 0 views
  • 29 Oct, 2022
  • 1 location
The Effects of Cold Adaptation on Skin Blood Flow, Hand Function, and Comfort in Healthy Adults

elicits an adaptive habituation response that is characterized by blunted skin vasoconstriction and thus may be an effective strategy to improve peripheral perfusion, reduce thermal discomfort, and

Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 1 location
Potential Effects of Electronic Nicotine Delivery System Flavor Regulations on African American Menthol Smokers (RVA Flavors)

, toxicant exposure, and abuse liability among African American menthol smokers.

Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 1 location
Clinical Trials of Multivalent Opioid Vaccine Components

oxycodone [Oxy(Gly)4-sKLH], one of the most commonly abused prescription opioids. The vaccination approach to treating substance use disorders relies on the ability of the vaccine to produce antibodies that

Accepts healthy volunteers
  • 31 views
  • 04 Oct, 2022
Free-Base Nicotine or Nicotine Salt e-Liquids in Current E-Cigarette Smokers, PeloPET Study

This clinical trial studies the effect of free-base compared with nicotine salt based e-liquids on electronic cigarette (EC) puffing behavior, abuse liability, and deposition and absorption of

  • 21 views
  • 04 Oct, 2022
  • 1 location
Development of Neuroimaging Methods to Assess the Neurobiology of Addiction

alcoholism or drug abuse. Participants will answer questions to see if they can participate in MRI. Participants will have MRI scans. The scanner is a metal cylinder in a strong magnetic field

Accepts healthy volunteers
  • 572 views
  • 25 Oct, 2022
  • 1 location