Sinus Infections Clinical Trials

A listing of Sinus Infections medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 44 clinical trials
Featured trial
Dupilumab in CRSsNP (Liberty CRSsNP ORION)  

of dupilumab to reduce the incidence of participants with CRSsNP worsening/acute sinusitis who require treatment with antibiotics, systemic corticosteroids (SCS) or sinus surgery compared to placebo

congestion
acute sinusitis
facial pain
sinus surgery
obstruction
  • 20 views
  • 31 Jan, 2023
  • 8 locations
Featured trial
ENLIGHTEN 1: A Phase III, Randomized, Blinded, Controlled, Parallel-Group Trial to Evaluate the Efficacy and Safety of LYR-210 for the Treatment of Chronic Rhinosinusitis (CRS) in adults

Evaluates the safety and efficacy of the LYR-210 matrix in patients with chronic rhinosinusitis without nasal polyps

nasal polyps
rhinosinusitis
  • 2 views
  • 07 Mar, 2022
  • 1 location
Featured trial
A Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate CBP-201 in Adult Patients with Chronic Rhinosinusitis with Nasal Polyps

To evaluate the efficacy of CBP-201 in patients with chronic rhinosinusitis with nasal polyps 

nasal polyps
rhinosinusitis
  • 15 views
  • 07 Mar, 2022
  • 1 location
Featured trial
A Multicentre, Randomised, Double-Blind, Parallel-Group, Placebo-Controlled Phase 3 Efficacy and Safety Study of Tezepelumab in Participants with Severe Chronic Rhinosinusitis with Nasal Polyposis

A Multicentre, Randomised, Double-Blind, Parallel-Group, Placebo-Controlled Phase 3 Efficacy and Safety Study of Tezepelumab in Participants With Severe Chronic Rhinosinusitis With Nasal Polyposis (WAYPOINT)

  • 0 views
  • 17 Feb, 2022
  • 1 location
Effect of Novel Exhalational Delivery System With Fluticasone (EDS-FLU) on Eustachian Tube Dysfunction (ETD)

Intranasal nasal steroid sprays are the mainstay of treatment for chronic Eustachian tube dysfunction despite having little supportive evidence in the literature. A novel, commercially available nasal spray delivery system is available now for fluticasone that improves its delivery to the nasopharynx. The hypothesis of this study is that fluticasone …

Accepts healthy volunteers
  • 23 views
  • 07 Oct, 2022
  • 2 locations
A Randomized Controlled Trial of Deflazacort vs. Prednisolone in Acute-stage Allergic Bronchopulmonary Aspergillosis

Oral glucocorticoids are currently the treatment of choice for allergic bronchopulmonary aspergillosis (ABPA). They not only suppress the immune hyperfunction but are also anti-inflammatory. Unfortunately, numerous toxicities and adverse effects have been attributed to glucocorticoids related to both the average dose and cumulative duration of use. Deflazacort is a oxazoline …

  • 199 views
  • 23 Oct, 2022
  • 1 location
Dupilumab in CRSsNP (Liberty CRSsNP ORION)

to reduce the incidence of participants with CRSsNP worsening/acute sinusitis who require treatment with antibiotics, systemic corticosteroids (SCS) or sinus surgery compared to placebo To

congestion
acute sinusitis
facial pain
sinus surgery
obstruction
  • 47 views
  • 25 May, 2022
  • 48 locations
Improving Antibiotic Use in Urgent Care Facilities (SCORE_UC)

This study will implement a comprehensive outpatient stewardship program targeting a large network of Urgent Care (UC) clinics within Intermountain Helathcare.

Accepts healthy volunteers
  • 0 views
  • 19 Apr, 2022
  • 1 location
Endoscopic Sinus Surgery in Recurrent Acute Rhinosinusitis

The aim of this study is to find out if endoscopic sinus surgery improves the quality of life in patients suffering from recurrent acute rhinosinusitis. Our main outcome is the difference between the average change in disease-specific SNOT-22 quality of life questionnaire scores (from baseline to 5-6 months follow-up) between …

congestion
acute sinusitis
sinus surgery
antibiotic therapy
acute rhinosinusitis
  • 174 views
  • 25 Feb, 2022
  • 1 location
Microbiota Transfer for Chronic Rhinosinusitis (SNMT)

Chronic sinusitis (CRS) is a common inflammatory condition of the sinuses that affects up to 2.5% of the Canadian population, and is thought to be caused by bacterial infection, resistant

rhinosinusitis
antibiotics
facial pain
sinus surgery
chronic sinusitis
  • 0 views
  • 04 Oct, 2022
  • 1 location