HIV Infections Clinical Trials

A listing of HIV Infections medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 353 clinical trials
Prevention of OUD: The HOME (Housing, Opportunities, Motivation and Engagement) Randomized Trial (HOME)

country (Brands et al., 2005); heroin using homeless youth also appear to have the highest rates of IV drug use and HIV (Rhoades et al., 2014). Given the high rates of opioid use, exposure to violence

Accepts healthy volunteers
  • 8 views
  • 23 Oct, 2022
  • 1 location
A Multicenter Phase II Study of Pomalidomide Monotherapy in Kaposi Sarcoma

This phase II trial studies the effect of pomalidomide in treating patients with Kaposi sarcoma. Pomalidomide is a cancer fighting drug that stops the growth of blood vessels, stimulates the immune system, and may kill cancer cells.

  • 0 views
  • 27 Oct, 2022
  • 2 locations
Intermittent Oral Naltrexone Enhanced With an Ecological Momentary Intervention for Methamphetamine-using MSM

This is a double-blind, placebo-controlled phase 2b trial in which 54 MSM who use meth will be randomly assigned (2:1) to receive 12 weeks of as-needed intermittent oral naltrexone 50 mg enhanced with an EMA-informed EMI platform, or receive as-needed placebo with EMA-informed EMI. The 12-week treatment period is consistent …

Accepts healthy volunteers
  • 0 views
  • 07 Oct, 2022
  • 1 location
VEN-OM: Phase IB/II Study Of Safety And Efficacy Of Venetoclax When Combined With Escalating Doses Of Omacetaxine In Patients With Relapsed/Refractory Hematologic Malignancies Failing Treatment With Venetoclax-Containing Regimens (VEN-OM)

This will be a single arm, open label Phase Ib dose-escalation study of the combination of VEN and OM, conducted using an innovative Bayesian Optimal Interval-design, to find the MTD in participants with relapsed/refractory hematologic malignancies including those failing treatment with venetoclax-containing regimens. Treatment plan will consist of an induction …

  • 0 views
  • 13 Oct, 2022
  • 1 location
Encochleated Oral Amphotericin for Cryptococcal Meningitis Trial (EnACT) (EnACT)

This study is designed as two sequential trials. The first is a phase I open label trial to evaluate the safety and tolerability of MAT2203. The maximal tolerated and non-toxic daily dose,will then be moved forward into a multi-day safety trial. The Phase II trial will investigate toxicity and early …

multi-day
flucytosine
amphotericin b
mat2203
csf cryptococcal antigen
  • 132 views
  • 07 Oct, 2022
  • 1 location
Study of Ruxolitinib in Solid Organ Transplant Recipients With Advanced Cutaneous Squamous Cell Carcinoma

In this open-label, multicenter, Phase II study, the investigators propose to evaluate the efficacy of ruxolitinib, an orally administered inhibitor of JAK1/2, in solid organ transplant recipients with advanced cSCC. In a safety lead-in of 6 patients, subjects will receive ruxolitinib 15mg twice daily (BID). After 4 weeks, if dose-limiting …

  • 0 views
  • 04 Oct, 2022
  • 2 locations
Fecal Microbiota Transplantation in Refractory Clostridium Difficile Colitis

It has been shown that restoration of the normal makeup of the bowel bacterial population is the most effective way to treat recurrent colitis due to Clostridium difficile. Restoration of the normal bowel bacterial population is best done by transplanting stool from a healthy donor. The investigators wish to transplant …

clostridium difficile
microbiota
  • 0 views
  • 19 Oct, 2022
  • 1 location
The Effect of Stem Cells and Stem Cell Exosomes on Visual Functions in Patients With Retinitis Pigmentosa

This clinical trial aims to study the efficacy of umbilical cord-derived mesenchymal stem cells and their exosomes in the treatment of retinitis pigmentosa. The participants will be randomized into 3 groups. Functional and structural parameters will be compared before and after the injections and also will be compared among the …

electroretinogram
genetic analysis
corrected visual acuity
  • 0 views
  • 07 Oct, 2022
  • 1 location
Doravirine (DOR) in Human Immunodeficiency Virus (HIV)-Infected Children Ages 4 Weeks to <12 Years and <45 kg (MK-1439-066)

This is a single-group, open-label, multi-site study in pediatric participants with human immunodeficiency virus type 1 (HIV-1) infection, aged 4 weeks to <12 years and weighing <45 kg

antiretroviral therapy
HIV Vaccine
tenofovir
hiv-1 rna measurement
immunodeficiency
  • 0 views
  • 07 Oct, 2022
  • 13 locations
Effectiveness of a Smoking Cessation Algorithm Integrated Into HIV Primary Care

To determine the efficacy of an algorithm designed to recommend smoking cessation-related pharmacotherapy options to the primary care providers of smokers living with HIV/AIDS.

HIV Vaccine
bupropion
smoking cessation
nicotine patch
varenicline
  • 0 views
  • 07 Oct, 2022
  • 1 location