Heartburn Clinical Trials

A listing of Heartburn medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 23 clinical trials
Effect of MIST on Esophageal Sensitivity in HV (MIST)

Effect of acute psychosocial stress on esophageal sensitivity in healthy volunteers.

Accepts healthy volunteers
  • 0 views
  • 10 Jul, 2022
  • 1 location
Effect of MIST on Esophageal Sensitivity in Patients With rGERD (MIST)

Effect of acute psychosocial stress on esophageal sensitivity in patients with refractory gastro-esophageal reflux disease and healthy volunteers.

  • 0 views
  • 13 Jul, 2022
  • 1 location
A Food Additive Removal Diet for Pediatric Eosinophilic Esophagitis (FREE)

Prospective, pragmatic standard of care clinical trial comparing dietary therapies of standard dairy elimination diet alone (DED) to dairy elimination plus food additive elimination (FREE)

elimination diet
eosinophilia
  • 7 views
  • 23 Apr, 2022
  • 2 locations
A Study to Evaluate the Efficacy and Safety of Vonoprazan Compared to Placebo for Relief of Heartburn in Participants With Symptomatic Non-Erosive Gastroesophageal Reflux Disease (NERD)

The primary objectives of this study are to assess the efficacy of vonoprazan (10 mg and 20 mg once daily [QD]) compared to placebo (QD) in relief of heartburn over 4 weeks in participants with

burning sensation
reflux
gastroesophageal reflux
  • 19 views
  • 05 Jul, 2022
  • 80 locations
Tolerability Study of Panosyl-Isomaltooligosaccharides (PIMO) and a Placebo in Subjects With Heartburn

Remote un-controlled trial to evaluate the tolerability of MHS-1031 and separately the tolerability of the formulated placebo in subjects with heartburn. Candidates will have heartburn and be

Accepts healthy volunteers
  • 0 views
  • 17 May, 2022
Genotype-tailored Treatment of Symptomatic Acid-Reflux in Children With Uncontrolled Asthma (GenARA)

This study will evaluate the effect of CYP2C19 and ABCB1 genes on pharmacokinetics of lansoprazole in children with mild gastroesophageal reflux (GER) and uncontrolled asthma. It will determine if genotype-guided lansoprazole dosing of lansoprazole improves GER and asthma control.

lansoprazole
corticosteroids
fluticasone
  • 18 views
  • 19 Jun, 2022
  • 2 locations
Blinded Dry Mouth Spray Crossover Study

of life and mouth acidity following use of two mouth sprays meant to relieve symptoms of xerostomia in patients who have received radiation for carcinoma of the head and neck.

carcinoma
  • 2 views
  • 27 Jul, 2022
  • 2 locations
A Study of Multiparametric MRI and pHLIP® ICG in Breast Cancer Imaging During Surgery

acidity of the tumor than standard MRI, and to see whether the use of the fluorescent imaging agent pHLIP ICG and NIRF imaging during surgery is a safe approach that may allow the surgeon to see the tumor

mammogram
  • 0 views
  • 08 Jun, 2022
  • 1 location
Domperidone in Treating Patients With Gastrointestinal Disorders

This phase III trial studies how well domperidone works in treating patients with gastrointestinal disorders. Domperidone may help control chronic gastrointestinal disorders and their symptoms, such as pain, bloating, and nausea and vomiting, by stimulating contraction of the stomach to increase its ability to empty itself of food.

heartburn
gastrointestinal disease
respiratory symptoms
dyspepsia
urea
  • 1561 views
  • 12 May, 2022
  • 1 location
The Effect of Positional Therapy on Symptoms of Gastroesophageal Reflux Disease: A Prospective Pilot Study

) accompanied by acid reflux, as compared with the left recumbent position. Moreover, maintaining the left lateral recumbent position, reduced by 87% esophageal acid exposure and nocturnal symptoms.

Accepts healthy volunteers
  • 0 views
  • 23 Apr, 2022
  • 1 location