Circulation Disorders Clinical Trials

A listing of Circulation Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 10 clinical trials
A Research Study to Compare a Medicine Called Semaglutide Against Placebo in People With Peripheral Arterial Disease and Type 2 Diabetes (STRIDE)

This study is done to see if semaglutide has an effect on walking ability compared with placebo (dummy medicine) in people with peripheral arterial disease (PAD) and type 2 diabetes. Participants will either get semaglutide or placebo ("dummy") medicine - which treatment participants get is decided by chance. Semaglutide is …

intermittent claudication
  • 09 Apr, 2023
  • 111 locations
A Clinical Evaluation of the MicroSTent® PeripherAl Vascular SteNt in Subjects With Arterial Disease Below the Knee (STAND)

Randomized multicenter clinical trial consisting of two arms; one arm treated with PTA plus the MicroStent® System and one arm treated with PTA alone. Purpose to evaluate the safety and effectiveness of using the MicroStent® Peripheral Vascular Stent System, hereafter referred to as the MicroStent® System, for the treatment of …

vascular disease
limb ischemia
  • 23 Oct, 2022
  • 16 locations
Smartstep Smartphone PAD (SMARTSTEP)

The study aim is to evaluate the effectiveness of a coached, smartphone-enabled exercise program versus physician directed exercise therapy (usual care).

exercise therapy
intermittent claudication
  • 07 Oct, 2022
  • 1 location
Assessment of the Utility of the Pantheris Small Vessel (SV) System

A single-arm study to assess the utility of the Pantheris SV catheter in addressing peripheral artery disease in arteries located below the knee. Data will be collected on the percent stenosis pre- and post-atherectomy and then symptoms and adverse events noted at 30 days, 6 months, and 1 year after …

  • 08 Apr, 2023
  • 2 locations
Peripheral Nerve Blocks for Upper Leg Amputations

Surgery performed with nerve blocks and sedation may be safer and provide better pain control compared to general anesthesia and opioid therapy in high-risk patient populations such as elderly and troubled with peripheral vascular disease, diabetes, hypertension, coronary artery disease, and chronic obstructive pulmonary disease (COPD).

peripheral vascular disease
vascular disease
chronic obstructive pulmonary disease
  • 18 Oct, 2022
  • 1 location
A Clinical and Histological Analysis of Mesenchymal Stem Cells in Amputation (CHAMP)

Patients undergoing semi-elective lower extremity major amputation from complications associated with atherosclerotic limb ischemia will received intra-muscular injections of allogeneic Mesenchymal Stromal Cells in the leg above and below the point of amputation to prevent ischemic wound complications after surgery and decrease the incidence of revision and further amputation. Cohort …

limb ischemia
ischemic wound
  • 21 Oct, 2022
  • 1 location
Drug-Eluting Registry: Real-World Treatment of Lesions in the Peripheral Vasculature (ELEGANCE)

The ELEGANCE Registry's objective is to collect Real-World Data (RWD), including populations previously not represented in Peripheral Vascular Disease (PVD) trials, health economics data, and to support the safe use of commercially available Boston Scientific Corporation (BSC) drug-eluting devices for the treatment of lesions located in the peripheral vasculature.

percutaneous transluminal angioplasty
peripheral vascular disease
transluminal angioplasty
  • 03 Apr, 2023
  • 52 locations
OEIS (Outpatient Endovascular and Interventional Society) Outcome Data Registry

This registry is created under the sponsorship of the Outpatient Endovascular and Interventional Society (OEIS) to monitor the clinical course and treatment outcomes of patients undergoing office-based endovascular procedures.

vascular disease
endovascular procedure
  • 15 Oct, 2022
  • 1 location
The Mechanical Characterisation of Human Saphenous and Popliteal Vein

Non-interventional study aiming to ascertain the mechanical properties of human saphenous and popliteal vein tissue.

  • 03 Apr, 2023
  • 1 location
Metabolomic Analysis of Systemic Sclerosis (SCLEROMICS)

Currently investigators do not have diagnostic and prognostic markers for SSc which almost always starts with a vascular disease (Raynaud's disease) isolated for several years. The primary purpose is to highlight discriminating metabolic profiles depending on the characteristics of the disease, allowing early diagnosis of SSc at the onset of …

raynaud's syndrome
early diagnosis
vascular disease
  • 04 Oct, 2022
  • 3 locations