High Cholesterol (Hyperlipidemia) Clinical Trials

A listing of High Cholesterol (Hyperlipidemia) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 71 clinical trials
A Nurse-led Intervention to Extend the HIV Treatment Cascade for Cardiovascular Disease Prevention

Strategies to improve uptake of cardiovascular disease preventive therapies among people living with HIV (PLHIV) are urgently needed. This study tests an innovative prevention nurse intervention to extend the HIV/AIDS treatment cascade for the treatment of hypertension and hyperlipidemia among PLHIV on suppressive antiretroviral therapy. This intervention may be scalable …

coronary artery disease
antihypertensive drugs
antiretroviral therapy
antiretroviral agents
diabetes
  • 0 views
  • 25 Jan, 2021
  • 2 locations
Statins in Reducing Events in the Elderly (STAREE) Heart Sub-study

The STAREE-HEART sub-study will examine the effect of statin treatment over a 3-year period compared with placebo on markers of cardiac ageing. This will include determining global longitudinal strain with transthoracic echocardiography, atrial fibrillation with home measures twice daily for two weeks and changes in biomarkers.

12 lead ECG
electrocardiogram
heart study
hmg-coa reductase inhibitors
diagnostic procedure
  • 8 views
  • 26 Jan, 2021
  • 1 location
Combined Effect of Acitretin and Narrow Band Ultraviolet B on Vitiligo Repigmentation

Since abnormal keratinocyte (KC) proliferation and differentiation as well as defective E cadherin expression were reported in vitiligo lesions, the investigators set to study the potential efficacy of combining Retinoids, which are known to improve KC proliferation and differentiation and increase the expression of adhesion molecules, with narrowband UVB in …

  • 36 views
  • 29 Jul, 2021
  • 1 location
Acute Probiotic Supplementation and Endothelial Function

One in every two deaths in the United States is caused by cardiovascular disease. Despite strong mechanistic links established between a diet rich in lipids and the pathogenesis of cardiovascular disease, therapeutic advances have focused on reduction in either ingestion or synthesis of cholesterol, and reduction in dietary trans and …

diabetes
endothelial dysfunction
cerebrovascular disease
hmg-coa reductase inhibitor
cardiovascular disease
  • 12 views
  • 05 Sep, 2021
  • 1 location
The Combined Portfolio Diet and Exercise Study

The purpose of this study is to determine whether a dietary portfolio of cholesterol-lowering foods (viscous fibres, soy protein, plant sterols and nuts) further enhanced by increased levels of monounsaturated fatty acids (MUFA) and low glycemic index foods; together with a structured exercise program reduce the progression of carotid and …

diabetes
fats
hmg-coa reductase inhibitor
low density lipoprotein
statin
  • 209 views
  • 23 Jan, 2021
  • 4 locations
Effect of Probiotics in Non-alcoholic Fatty Liver Disease and Steatohepatitis

This study will evaluate the effect of probiotics, a beneficial intestinal bacteria supplement, if it will cause improvement of the non-alcoholic fatty liver disease (NAFLD) and or non-alcoholic steatohepatitis (NASH- an inflammation with concurrent fatty accumulation of the liver) as measured by transient elastography - an ultrasound of the liver …

  • 0 views
  • 24 Apr, 2021
  • 1 location
Multiple Ascending Dose Study to Evaluate the Safety Tolerability of DC371739 Treatment in Hypercholesterolemic

This study is to evaluate safety, tolerability, pharmacokinetics and pharmacodynamics of DC739 after multiple-dose oral administration, to explore the clinical effective dose, and to initially explore the efficacy and safety in hypercholesterolemia subjects.

hypercholesterolemia
body mass index
  • 0 views
  • 23 Jun, 2021
  • 1 location
Omega-3 Fatty Acid Dietary Intervention (O3DI)

Elevated cholesterol, including triglyceride levels, can lead to the development of cardiovascular disease in adulthood. A diet that is rich in omega-3 fatty acids (O3FA) can improve triglyceride levels in a way that is safe and does not require medication. This is a single-center, prospective, unblinded, randomized-controlled dietary intervention study …

cholesterol level
fatty acids
cardiovascular disease
omega-3 fatty acids
serum triglycerides
  • 0 views
  • 05 Sep, 2021
  • 1 location
Effects of Replacing Energy From Solid Fats and Added Sugars (SoFAS) With Avocado

The objective of this study is to assess the effects of replacing energy from SoFAS with energy from avocado on non-high-density lipoprotein cholesterol (non-HDL-C) and other aspects of the cardiometabolic health profile including fasting lipoprotein lipid and particle concentrations, insulin sensitivity and blood pressure in men and women with elevated …

fasting
nicotine-containing product
lipoprotein cholesterol
fats
insulin sensitivity
  • 0 views
  • 15 Aug, 2021
  • 2 locations
Efficacy and Safety of Evinacumab in Adult Patients With Severe Hypertriglyceridemia for the Prevention of Recurrent Acute Pancreatitis

The primary objective of the study is to determine the proportion of patients with triglycerides (TG) >880 mg/dL, without familial chylomicronemia syndrome (FCS) due to loss of function (LoF) mutations in lipoprotein lipase (LPL), and a history of hypertriglyceridemia (HTG)-associated acute pancreatitis (AP) who experience a recurrent episode of AP …

fasting
lipid-lowering therapy
body mass index
pancreatitis
  • 0 views
  • 31 Jul, 2021
  • 2 locations