High Cholesterol (Hyperlipidemia) Clinical Trials

A listing of High Cholesterol (Hyperlipidemia) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 71 clinical trials
Food Pharmacy at Oregon Health & Science University (OHSU) Knight Cardiovascular Institute (KCVI)

Participants in the intervention group of this study will receive weekly home deliveries of fruit & vegetables for 3 months. The primary objective of this study is to determine if increased access to fruits and vegetables leads to sustained dietary changes, measured through changes in the Healthy Eating Index (HEI). …

glycosylated hemoglobin
hemoglobin a1c
blood lipids
body mass index
  • 3 views
  • 26 Jan, 2021
  • 1 location
Plasma Lipoprotein Response to Glucagon-like Peptide-2

Some of the fat (triglyceride) from the food humans eat gets stored in the bowel. This triglyceride can then be released into the blood when another meal is consumed or in response to hormones. How the gut hormone glucagon-like peptide-2 (GLP-2) releases the triglyceride from the gut is not known. …

glucagon
glp-2
gut hormone
body mass index
  • 1 views
  • 11 May, 2021
  • 1 location
Effects of Oral Glucose and Teduglutide on Plasma Lipoproteins

Some of the fat (triglyceride) from the food humans eat gets stored in the bowel. This triglyceride can then be released into the blood when another meal is consumed or in response to hormones. How the gut hormone glucagon-like peptide-2 (GLP-2) and glucose release the triglyceride from the gut is …

glucagon
glp-2
gut hormone
body mass index
  • 2 views
  • 05 May, 2021
  • 1 location
Safety and Efficacy of CVI-LM001 in Patients With Hypercholesterolemia

The purpose of this study is to determine if CVI-LM001 is effective and safe versus placebo in drug-naive subjects with elevated LDL cholesterol. There will be 4 groups receiving 100mg, 200mg, 300 mg and placebo treatment for 12 weeks respectively.

cholesterol measurement
low density lipoprotein
cholesterol level
LDL Cholesterol
hypercholesterolemia
  • 37 views
  • 25 Jan, 2021
  • 2 locations
To Evaluate the Efficacy and Safety of JS002 in HoFH Patients

JS002 is a recombinant human anti-PCSK9 monoclonal antibody. This phase II open-label, single-arm study aims to evaluate the efficacy and safety of JS002 in patients with homozygous familial hypercholesterolemia A dose group (450 mg) was set up in this study.Thirty subjects are planned to be enrolled. Each subject required a …

  • 0 views
  • 17 Mar, 2021
  • 1 location
Study of Pharmacokinetics Pharmacodynamics Safety and Tolerability of Inclisiran in Chinese Participants With Elevated Serum LDL-C

Study to evaluate the pharmacokinetics and pharmacodynamics of inclisiran treatment given as single subcutaneous injection in Chinese participants with elevated low-density lipoprotein cholesterol (LDL-C) despite treatment with LDL-C lowering therapies

ezetimibe
cholesterol measurement
serum low density lipoprotein
cholesterol level
hmg-coa reductase inhibitors
  • 0 views
  • 11 Jul, 2021
  • 2 locations
Lipid Management in Renal Transplant Recipients Using Evolocumab.

Cardiovascular disease is the leading cause of mortality after renal transplantation, accounting for more than 30% of deaths. Elevated lipid levels (hyperlipidemia) are a frequent finding following transplantation and the immunosuppressive medications play a central role in the development or worsening of hyperlipidemia. In the general population, the correlation between …

  • 0 views
  • 13 May, 2021
  • 1 location
Efficacy of Ethyl Icosapentate in Patients With Severe Hypertriglyceridemia

The purpose of this study is to evaluate the efficacy and safety of ethyl icosapentate in Chinese patients with severe hypertriglyceridemia.

serum triglycerides
fasting
icosapent ethyl
  • 8 views
  • 29 Aug, 2021
  • 1 location
Kefir Cholesterol Lowering Pilot Study

High cholesterol (a type of fat in humans blood) may be one factor that can lead to heart disease. If people have higher cholesterol, it is possible that kefir (a food similar to yogurt) may help to control blood cholesterol levels.

dyslipidemia
blood cholesterol
cholesterol measurement
heart disease
diabetes
  • 239 views
  • 25 May, 2021
  • 3 locations
Postprandial Monocyte Maturation and Vascular Dysfunction Following High-Fat Meals - Study 1

The purpose of this research study is to examine the effect of high-fat meals on the health of blood vessels. In addition, the study will examine how exercise/fitness/physical activity impacts blood vessels after consumption of a high-fat meal.

exercise test
fasting
  • 1 views
  • 26 Jan, 2021
  • 1 location