High Cholesterol (Hyperlipidemia) Clinical Trials

A listing of High Cholesterol (Hyperlipidemia) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 10 clinical trials
Featured trial
A randomized, double-blind, placebo-controlled multicenter trial, assessing the impact of inclisiran on major adverse cardiovascular events in participants with established cardiovascular disease

We are seeking participants for a clinical research study who have Atherosclerotic Cardiovascular Disease (thickening/hardening of the arteries which is caused by a buildup of plaque in the lining of an artery).This study is designed to evaluate the treatment of an investigational medication along with a well-tolerated statin therapy (lipid …

hmg-coa reductase inhibitor
atherosclerotic cardiovascular disease
stroke
  • 0 views
  • 31 May, 2022
  • 1 location
Study to Investigate Safety, Tolerability, PK and PD Response of SLN360 in Subjects With Elevated Lipoprotein(a)

This study will investigate the safety and tolerability of SLN360 in patients with elevated Lp(a).

body mass index
cardiovascular disease
  • 0 views
  • 07 Apr, 2022
  • 7 locations
Lipid Management in Renal Transplant Recipients Using Evolocumab.

Cardiovascular disease is the leading cause of mortality after renal transplantation, accounting for more than 30% of deaths. Elevated lipid levels (hyperlipidemia) are a frequent finding following transplantation and the immunosuppressive medications play a central role in the development or worsening of hyperlipidemia. In the general population, the correlation between …

  • 0 views
  • 22 Jul, 2022
  • 1 location
A First in Human Study of STT-5058, an Antibody That Binds ApoC3

A First in Human Study of STT-5058, an Antibody That Binds ApoC3, investigating single and multiple ascending intravenous doses and ascending subcutaneous doses of STT-5058 in otherwise healthy volunteers with elevated triglyceride levels

monoclonal antibody
fasting
  • 66 views
  • 08 Jul, 2022
  • 1 location
Efficacy of Ethyl Icosapentate in Patients With Severe Hypertriglyceridemia

The purpose of this study is to evaluate the efficacy and safety of ethyl icosapentate in Chinese patients with severe hypertriglyceridemia.

fasting
serum triglycerides
icosapent ethyl
  • 45 views
  • 28 Jun, 2022
  • 1 location
Impacts of Lentils on Metabolism and Inflammation

The overall goal of this investigation is to determine gut microbiome dependent and independent impacts of pulse consumption on metabolic resilience and metabolic risk profiles for type 2 diabetes (T2D) and cardiovascular disease (CVD) risk. Specifically, pulse crop consumption has unrealized potential to fundamentally alter how the body responds to …

fats
fasting
serum triglycerides
cardiovascular disease
type 2 diabetes mellitus
  • 436 views
  • 19 Jun, 2022
  • 1 location
Soy Modulation of Immune Activation, LDL- Levels, and Lowering Inflammation by Pretzel Isoflavone Dietary Intervention (SMALL LIPIDS)

Combination antiretroviral therapy (ART, HIV medications) dramatically increases the expected lifespan of HIV (Human Immunodeficiency Virus)infected patients; yet, the risks for cardiovascular disease (CVD), such as heart attacks and stroke, are increased in this population. This increased risk may be linked to persistent inflammation and activation of the immune system. …

enzyme-linked immunosorbent assay
antiretroviral therapy
atazanavir
hiv-1 antigen
immunodeficiency
  • 11 views
  • 14 May, 2022
  • 1 location
Compassionate Use of Metreleptin in Previously Treated People With Generalized Lipodystrophy

Background Generalized lipodystrophy can cause high blood fat levels and resistance to insulin. This can lead to health problems including diabetes. Researchers have found that the drug metreleptin improves health in people with this disease. Objective To test the safety and effectiveness of metreleptin. Eligibility People ages 6 months and …

blood test
diabetes
sweet
x-rays
metreleptin
  • 14 views
  • 26 Jul, 2022
  • 1 location
Study of Awareness and Detection of Familial Hypercholesterolemia (CASCADE-FH)

The CASCADE-FH Registry is a national, multi-center initiative that will track the therapy, clinical outcomes, and patient-reported outcomes over time. The registry represents a collaboration between The Familial Hypercholesterolemia Foundation, the Duke Clinical Research Institute, lipid specialists, cardiologists, primary care providers, quality improvement personnel, and patients, all aiming to increase …

familial hypercholesterolemia
cholesterol measurement
hypercholesterolemia
  • 39 views
  • 10 May, 2022
  • 1 location
Causes and Natural History of Dyslipidemias

This study will evaluate people with dyslipidemias - disorders that affect the fat content in the blood. Fats, or lipids, such as cholesterol and triglycerides, are carried in the blood in particles called lipoproteins. These particles are involved in causing blood vessel diseases that can lead to conditions like atherosclerosis …

xanthoma
familial hypercholesterolemia
plasma cholesterol
cholesterol level
dyslipidemia
  • 47 views
  • 29 Jul, 2022
  • 1 location