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Atherosclerosis Clinical Trials

A listing of Atherosclerosis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (100) clinical trials

The Effect of Tongguan Capsule for MicroRNA Profiles in Coronary Heart Disease Patients

The primary end points is the core of the whole experiment scheme. miRNAs regulate gene expression posttranscriptionally by degrading messenger RNA (mRNA) targets and by blocking their translation Secondary endpoints will include The adverse cardiac clinical events (MACE) in terms of cardiac death,periprocedural myocardial infarction (MI),spontaneous MI and target vessel ...

Phase

Optimizing Timing of CABG in Patients Presenting With ACS and Treated With Ticagrelor

The administration of Ticagrelor have demonstrated superiority to Clopidogrel in patients presenting with acute coronary syndrome (ACS) and remains a first line therapy as an adjunct to aspirin for patients admitted with ACS. The patient population treated with Ticagrelor at an early time point includes non ST elevation myocardial (NSTEMI) ...

Phase

Plasma and Platelet microRNAs in Clopidogrel Low Response Patients

A multiphase, case-control study was designed to identify plasma and platelet miRNAs as surrogate markers for CLR . All patients take 300mg loading dose clopidogrel plus 100mg daily ASA and 75mg daily clopidogrel after admission. Patients are recruited after percutaneous coronary intervention (PCI). Light transmittancy aggregation (LTA) in response to ...

Phase

Preventive Effects of Ginseng Against Atherosclerosis

The purpose of this study is to determine whether Ginseng is effective in the prevention of atherosclerosis and subsequent ischemic stroke.

Phase

Optimal Anti-platelet Treatment for Patients With Clopidogrel Low Response

Optimal anti-Platelet Treatment for patients with stent IMplantation And clopidogrel Low response: OPTIMAL study Previous studies showed that dual anti-platelet treatment (DAPT) with aspirin and clopidogrel provided 20% risk reduction for cardiovascular death, myocardial infarction and stroke compared with aspirin alone in patients with acute coronary syndrome (ACS)1-4. However, about ...

Phase

Intensive Statin Treatment in Acute Ischemic Stroke Patients With INtracranial Atherosclerosis

Purpose: Intracranial atherosclerosis is a common condition in Korean population consisting over 25% of ischemic stroke etiology. American Stroke Association and Korean Stroke Society recommend antiplatelet and statin for the treatment of intracranial atherosclerosis. Besides lowering blood cholesterol levels statin also stabilize atherosclerotic plaque and eventually lower the risk of ...

Phase

Subcutaneous Nitroglycerin to Facilitate Trans-radial Access.

Unlike femoral access, the trans-radial approach to coronary angiography requires a greater learning curve for the inexperienced interventionist, and demands a greater technical challenge than the femoral approach, which leads to a high incidence of failures and complications, mainly in the initial stages of their formation. Some explanations for procedural ...

Phase

Diagnostic Study of Rapid Regadenoson Stress Cardiovascular Magnetic Resonance (CMR) to Detect Coronary Artery Disease

This is a single center, open-label, pilot study in subjects scheduled for invasive coronary angiography for evaluation of coronary artery disease. The primary objective is to evaluate the profile of sensitivity, specificity, and diagnostic accuracy of a novel rapid regadenoson stress CMR protocol for detection of >= 70 coronary artery ...

Phase

Efficacy Study of Hydroxychloroquine to Treat High-risk Coronary Artery Disease.

This double blind, placebo, randomized controlled trial is going to assess if hydroxychloroquine could improve the high sensitivity C-reaction protein, blood lipid, blood glucose and blood pressure, also whether hydroxychloroquine could affect the secretion of inflammatory cytokines and the M1/M2 phenotype polarization of macrophages in patients with high-risk coronary artery ...

Phase

Hemostasis Pad Using Chitosan After Invasive Percutaneous Procedures

Arterial access is the key step during the endovascular treatment of cardiovascular diseases. However, failure in hemostasis of the arterial access sites is associated with high risk of complications such as bleeding, pseudoaneurysm, and arteriovenous fistula. Major bleeding events after percutaneous coronary intervention has been shown be associated with poor ...

Phase