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Atherosclerosis Clinical Trials

A listing of Atherosclerosis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (660) clinical trials

Percutaneous Coronary Intervention in Patients witH OrthotoPic hEart Transplantation: the PCI-HOPE a Multicenter Study.

Actual standard of care. Orthotopic heart transplantation (OHT) represents the optimal solution for the cure of end-stage heart failure, but it is burdened by numerous comorbidity. The main cause of morbidity and mortality in these patients is related to Transplant coronary artery disease (TCAD), that affects at least fifth percent ...

Phase N/A

Using Ultrasonography Shear Wave Elastography Strain Imaging and 3-D Volume Ultrasonography on Cardiovascular Disease

Aims, purpose, or objectives: To describe whether contrast-enhanced ultrasonography, strain imaging, and 3-D volume ultrasonography are helpful to characterize affected arteries and improve the imaging of arterial wall among patients with Fibromuscular Dysplasia (FMD) and segmental arterial mediolysis (SAM). Evaluate the arterial elastic properties of individuals with FMD and compare ...


XIENCE 28 Global Study

The XIENCE 28 Global Study will evaluate the safety of 1-month DAPT following XIENCE implantation in HBR patients. Approximately 800 subjects from approximately 50 sites globally will be registered in this trial. Eligibility of P2Y12 receptor inhibitor discontinuation will be assessed at 1-month follow-up. Subjects who are free from myocardial ...

Phase N/A

MyoStrain CMR Testing of Ischemia With Low Levels of Stress

This prospective, single center study evaluates the MyoStrain SENC CMR Imaging System for the detection of myocardial ischemia and viability during conventional Cardiac Magnetic Resonance (CMR) wall motion stress testing. Patients with known or suspected coronary artery disease and scheduled for cardiac catheterization will be consented for inclusion in the ...

Phase N/A

TEmporary Spinal CoRd StiMulatIon to PrevenNt Atrial FibrillaTION AFter Cardiac Surgery

The study includes 60 patients. Patients are randomized into 2 groups: coronary artery bypass grafting plus b-blocker treatment (according to guidelines; group I) and coronary artery bypass grafting plus b-blocker treatment (according to guidelines) plus temporary spinal cord stimulation (group 2). Temporary spinal cord stimulation is performed for 3 days ...

Phase N/A

Evaluation of CTCA in Assessing Plaque Pathology and Physiology

Cumulative evidence has demonstrated that plaque characteristics and vessel physiology are able to detect vulnerable plaques and identify high-risk individuals that are likely to suffer a cardiovascular event. The in vivo assessment of plaque morphology was traditionally performed using intravascular imaging techniques; however these modalities have significant limitations as: 1) ...

Phase N/A

Study to Evaluate the QT / QTc Interval Prolongation Potential of Vericiguat

The objective of this study is to evaluate the effect of multiple doses of vericiguat on the QTc interval in patients with stable CAD (coronary artery disease).


Rapid Eye Movement Related OSA in Diabetic Versus Non-Diabetic Patients Treated With PCI

The Sleep and Stent II is a cross-sectional study of patients who have undergone PCI for coronary artery disease. A total of 200 adult patients who have undergone clinically indicated PCI between 6 and 36 months ago are eligible. The study involves the 2 national heart centers in Singapore. The ...

Phase N/A

The Efficacy of Alirocumab for Thin-cap fIbroatheroma in Patients With Coronary Artery Disease Estimated by Optical Coherence Tomography

The investigators investigate to evaluate the efficacy of alirocumab for vulnerable plaque. The investigators enrolled the patient with standard statin therapy who were detected vulnerable plaque by optical coherence tomography, and categorized into two group; the patients with alirocumab and rosuvastatin were categorized alirocumab therapy group, and the patients with ...


Pilot Study-Magnetic Resonance Imaging for Global Atherosclerosis Risk Assessment

There are up to 2 study visits in this study. During the first visit, the investigators will obtain non-contrast MRI (carotid, coronary, and femoral) in 20 subjects with known coronary atherosclerosis but varying degrees of CVD risk. 5 asymptomatic subjects with lower CVD risk (recent coronary artery calcium score [CACS] ...

Phase N/A