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Atherosclerosis Clinical Trials

A listing of Atherosclerosis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (259) clinical trials

Molecular Determinants of Coronaruy Artery Disease

The purpose of this study is to discover genes that may cause Coronary Artery Disease (CAD) or Arteriovenous Malformation (AVM). Many human diseases are inherited or passed from parent to child in families. These diseases occur because of damage to a gene(s), the genetic material that is also called DNA. ...

Phase N/A

Italian Registry on Unprotected Left Main

The RITMO (Registro Italiano sul trattamento del Tronco coMune non protettO) observational study will be a prospective, multicenter, observational study aiming to appraise the prevalence, management strategy, and prognosis (up to 5 years) of unprotected left main coronary artery disease in Italy. A total of 45 Italian secondary and tertiary ...

Phase N/A

European Multicenter Randomized Comparative Efficacy/Safety Study of the Mar-Tyn TiN-Coated Stent

Occlusive coronary artery disease is predominantly caused by coronary atherosclerosis, a pathologic vascular condition characterized by abnormal lipid and fibrous tissue accumulation in the vessel wall. This condition may be accompanied by degenerative changes and/or calcification leading to stenosis (narrowing) of the luminal channel. Percutaneous Transluminal Coronary Angioplasty (PTCA) is ...

Phase

Effect of Short Term Atorvastatin Treatment 80mg/Day on Early Regression of Carotid Artery Atherosclerotic Lesions

Candidates for bilateral carotid endarterectomy (CEA) who meet study criteria will provide informed consent before their randomization. Before the first CEA, the patient will have MRI, US, and EBCT exams of both carotids. The most occlusive plaque will be resected at the first CEA. The patient will then receive atorvastatin ...

Phase

Clinical Feature and Outcome of Angiographic Coronary Artery Disease in Chronic Kidney Disease Patients

All patients who underwent cardiac catheterization for assessment of CAD at Keelung Chang Gung Memorial Hospital between 1992 and 2004 with continuous serum creatinine values measured before admission were included in this analysis. Data were obtained from medical records of the database center of our institution. Demographic and clinical data ...

Phase N/A

Anticoagulant Treatments and Percutaneous Coronary Angioplasty

- Background : We don't know if using IV anticoagulant therapy is necessary for percutaneous coronary angioplasty in stable patients. - Purpose : to compare efficacy and security of use or not of different anticoagulant treatments during percutaneous coronary angioplasty in patients with double antiaggregant therapy. - Abstract : In ...

Phase

Rho Kinase (ROCK) Inhibition in Carotid Atherosclerosis

To evaluate the causal relationship between Rho/Rho kinase overactivity and mechanisms of vascular dysfunction in patients with atherosclerosis.

Phase

Comparison of Coronary CT Angiography to Invasive Coronary Angiography

40 Patients who are scheduled to undergo coronary angiogram will be recruited at Mount Scopus and Ein Kerem. Patients will be excluded if they have one or more of the following conditions 1. CABG or stent implantation in the past. 2. Atrial fibrillation 3. Contraindication for beta blockers 1. Obstructive ...

Phase N/A

Clinical Application of MDCT in Coronary Artery Disease

Computed tomography is evolving as a tool for noninvasive diagnosis of coronary artery disease. Coronary calcium deposition amount is an established independent coronary artery disease risk factor. However, coronary artery stenosis seldom occurred in the same location as calcium deposition. With the advent of 16-detector-row multislice spiral CT, direct visualization ...

Phase

Treatment of Coronary Atherosclerosis by Insulin Sensitizers in Insulin-Resistant Patients

Background: Type 2 diabetes and its antecedent, metabolic syndrome, are important risk factors for premature and accelerated atherosclerotic cardiovascular diseases. However, glycemic control by provision of endogenous or exogenous insulin induced only modest and not statistically significant reduction of the risk of myocardial infarction. We and other investigators have demonstrated ...

Phase