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Atherosclerosis Clinical Trials

A listing of Atherosclerosis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (636) clinical trials

People with Atherosclerotic Lesions are asked to participate in a research study being conducted by Montefiore Medical Center.

Phase N/A

To evaluate the effectiveness of MicroVention Carotid Stent System used in conjunction with the Nanoparasol embolic protection system for the treatment of carotid artery stenosis in patients with elevated risk for adverse events following carotid endarterectomy.  The stent is a self-expanding implant with a rapid exchange delivery catheter. The Nanoparasol ...

Phase

This is a prospective, randomized one to one (1:1), multi-center trial designed to evaluate vessel preparation with Orbital Atherectomy (OA) compared to conventional balloon angioplasty technique prior to stent implantation for the treatment of severely calcified coronary artery lesions.  

Phase N/A

Research study to compare surgery, either a stent, or endarterectomy, and/or intensive medical management. Carotid arteries are the main arteries feeding your brain. The narrowing increases your risk of having a stroke. The narrowing is caused by a thickened area called a plaque.  

Phase N/A

The primary purpose of this study is to determine whether treatment with the Cobra PzF stent with 14 day Dual Anti-Platelet Therapy (DAPT) has a better safety profile compared to standard FDA approved Drug Eluting Stent plus 6-Month Dual Anti-Platelet Therapy in patients undergoing coronary intervention who also require oral ...

Phase N/A

The purpose of this study is to test the effects of taking alirocumab (Praluent) after stroke and if it could reduce the amount of intracranial atherosclerotic disease (ICAD), which we believe is what caused your stroke to happen. ICAD is known as hardening of the arteries, which occurs when the ...

Phase N/A

Over the past two decades, inflammation has been identified as an important pathogenic process in cardiometabolic diseases (CMD) such atherosclerotic cardiovascular disease (CVD), dyslipidemia, insulin resistance, diabetes and obesity. However, mechanistic links between inflammation and these disease states in humans remain poorly understood. In this study, we propose to utilize ...

Phase N/A

Biologically Modified Saphenous Vein Transplants for Improved CABG Outcomes

Double blind study with Lactated Ringers Solution and Lactated Ringers Solution with Arginine soaked for 10 minutes prior to grafting on the coronary arteries.

Phase

Identifying Vulnerable Plaques in Blood Vessels of the Heart Using a New Imaging Technique

Atherosclerosis is a condition in which deposits of fat, cholesterol, and other substances build up along the inner walls of arteries; these deposits are known as plaque. As plaque builds up, it increases the risk of heart attack. Previous autopsy studies have shown that vulnerable plaques, a type of atherosclerotic ...

Phase

Abnormal Coronary Vasomotion in Patients With Suspected Coronary Artery Disease (CAD)

In patients with chest pain and/or shortness of breath coronary artery disease (CAD) is suspected depending on the pattern of symptoms and the electrocardiogram (ECG). Coronary angiography is the method of choice to verify this suspicion. If the patient coronary arteries on coronary angiography are totally normal, one can only ...

Phase N/A