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Atherosclerosis Clinical Trials

A listing of Atherosclerosis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (11) clinical trials

Enhancing Cardiac Rehabilitation Through Behavioral Nudges

This study aims to (1) Iteratively develop and program a theoretically informed technology-based nudge message library for a diverse patient population using multiple and iterative N of 1 within subject studies. Investigators will also engage patient, provider and health systems stakeholders in designing and refining the messages; (2)Develop a one-page ...

Phase N/A

The FAVOR III China Study

The FAVOR III China is a prospective, multicenter, blinded, randomized, superiority clinical trial comparing the clinical outcome and cost-effectiveness of the two strategies, QFR-guided PCI versus standard angiography-guided PCI, in evaluation of patients with coronary artery disease (CAD). The study is adequately powered to detect if the primary outcome by ...

Phase N/A

Coronary Atherosclerosis T1-Weighted Characterization (CATCH)

Approximately 100 healthy male/female adult "normals" or "controls" and 40 male/female adult outpatients who are suspected of having or have been diagnosed with coronary artery disease will be recruited. All subjects will be asked to undergo either a non-contrast MRI or a contrast-enhanced MRI of the coronary artery depending upon ...

Phase N/A

Anatomical sNuffbox for Coronary anGiography and IntervEntions

Transradial approach has become the standard approach for coronary angiography (CAG) and percutaneous coronary intervention (PCI). The current ESC/EACTS guidelines of myocardial revascularization support using radial approach (RA) rather than femoral approach (FA) if the operators are experts for RA. Recently, an alternative transradial access has been suggested at the ...

Phase N/A

Targeting Mitochondrial Fusion and Fission to Prevent Atherosclerosis: Getting the Balance Right

Study 1 (tissue sample study): To investigate the changes in mitochondrial function and pro-inflammatory markers in human arterial atherosclerotic plaques. Hypothesis: Macrophages from femoral artery atherosclerotic plaques in patients with peripheral artery disease will display upregulation of mitochondrial fission proteins and features of pro-inflammatory activation. Study 2 (white blood cell ...

Phase N/A

Off-pump Versus On-pump Coronary Artery Bypass Grafting in Frail Patients

The FRAGILE protocol is a national multicenter randomized controlled trial (RCT), conducted in 8 Brazilian institutions. The study is already approved by a certified ethics committee. Funding is provided by a grant from So Paulo Research Foundation (FAPESP), which otherwise will not have any role in the conduct of the ...

Phase N/A

Frailty in Vascular Patients Undergoing Surgery

Vascular surgical operations are major procedures with significant associated morbidity and mortality. Frailty is a major factor influencing surgical outcome, but the effect on morbidity/mortality and quality of life is poorly understood in vascular surgery. Activity levels play a significant role in frailty and in pre-intervention preparation. It is anticipated ...

Phase N/A

Clinical Outcomes in Patients Treated With SternaLock Blu

The primary endpoint for this study is the rate of deep sternal wound infection (DSWI) at 30 days post-operative, following a midline sternotomy closed with SternaLock Blu. DSWI is defined as deep infection involving muscle, bone, and/ or mediastinum requiring operative intervention and has all of the following conditions: Wound ...

Phase N/A

Functional Assessment of Myocardial Ischemia by Intracoronary Electrocardiogram

INVASIVE PRESSURE-DERIVED INDICES OF STENOSIS SEVERITY In the setting of stable coronary artery disease (CAD), PCI or coronary artery bypass grafting (CABG) targets coronary lesions causing inducible myocardial ischemia. With the advancement of technology, the development of a coronary pressure guide wire enabled to reliably measure coronary perfusion pressure downstream ...

Phase N/A

The ENROUTE Transcarotid Neuroprotection System (ENROUTE Transcarotid NPS) DW-MRI Study

The ENROUTE Transcarotid NPS has received CE Mark and is commercially available in the European Union. The ENROUTE Transcarotid NPS may be used in conjunction with carotid artery stent approved for revascularization in patients with carotid disease in the context of this study. This is a prospective, single-arm, multi-center clinical ...

Phase N/A