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Atherosclerosis Clinical Trials

A listing of Atherosclerosis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (11) clinical trials

Education Model for Cardiac Patients

Randomized controlled trial (RCT) at a public teaching hospital, which has specialized care for CAD in Ribeiro Preto, state of So Paulo, Brazil. The intervention group will receive usual care and an educational programme and the control group will receive only usual care. One of the researchers will perform the ...

Phase N/A

Effect of Evolocumab on Coronary Endothelial Function

To evaluate the effect of the PCSK9 inhibitor evolocumab on coronary and systemic endothelial function, systemic biomarkers of endothelial function and of inflammation, and echocardiographic measures of left ventricular diastolic and systolic properties in subjects who are HIV+. Potential participants will be asked to undergo a screening MRI exam. Those ...


Prevalence of Familial Hypercholesterolaemia (FH) in Italian Patients With Coronary Artery Disease

Familial hypercholesterolemia (FH) is a disease that causes exposure to elevated plasma levels of LDL cholesterol (LDL-C, low-density lipoprotein) and increasing the risk of premature coronary heart disease (coronary artery disease, CAD). The FH is a co-dominant genetic disease and can occur in heterozygous and homozygous form, with different severity. ...

Phase N/A

Post-Operative Myocardial Incident & Atrial Fibrillation

To explore predictors of major cardio-vascular events after cardiac surgery and trans-catheter valve implantation with a specific interest in studying mechanisms linking pre-operative leukocyte, fat and myocardial phenotypes with post-intervention outcomes.

Phase N/A

Coronary Atherosclerosis Disease Early Identification and Risk Stratification by Noninvasive Imaging

The investigator prospectively enroll 30,000 outpatients who were suspected of coronary artery disease (CAD) and underwent cardiac computed tomography (CT). Cardiac CT was assessed for coronary artery calcification score (CACS) and the extent, the location, the stenosis severity, and the composition of the plaque in CTA. The base line information ...

Phase N/A

Clinical Trial of Efficacy and Safety of Divaza in the Management of Oxidative Disturbances in Cerebral Atherosclerosis

The diagnosis of "cerebral atherosclerosis" is established in the presence of all three causes: a) the main vascular disease and focal neurological symptoms in combination with cerebral symptoms; b) ultrasound signs of atherosclerotic lesion of the cerebrovascular bed (according to data of duplex scanning of the main arteries of the ...


Evaluation of Association Between Obstructive Sleep Apnea and the Severity of Coronary Artery Disease

Before initiating the study, all potential subjects were invited to attend an educational program that explained the purpose and methodology of this study. After getting informed consent from patients, demographic data including age, sex, medical history (including comorbidities and risk factors), current medicine, lifestyle habits, height (cm), and weight (kg) ...

Phase N/A

Effect of Alirocumab(Proprotein Convertase Subtilisin/Kexin type9 Inhibitor) and Rosuvastatin or Rosuvastatin Alone on Lipid Core Plaques in Coronary Artery Disease Evaluated by Near-infrared Spectroscopy Intravascular Ultrasound

We investigate the change in the maxLCBI (4 mm) value calculated by NIRS-IVUS at the time of PCI and at the treatment evaluation after 9 months compared with the group of Alirocumab(Alirocumab75mg/2week+losuvastatin10mg/daily) and standard treatment (losuvastatin10mg/daily alone). And also we evaluate LCBI(lesion), Angle of a lipid core, EEM CSA, Lumen ...


Endothelial Cell Gene Networks of CVD

The investigators propose to enroll CVD and healthy subjects between 30 and 60 years of age, matched for age, gender, body mass index, and medication (statin and anti-hypertensive) use. Circulating endothelial progenitor cells will be isolated from blood and cultured in vitro to differentiate into endothelial cells.

Phase N/A

Angiotensin-II Receptor Antibodies Blockade With Losartan in Patients With Lupus Nephritis

Angiotensin-II type 1 receptor antibodies (AT1R-Ab) are agonist antibodies directed against the second loop of the AT1 receptor. These antibodies have been studied in human diseases such as preeclampsia, transplantation and scleroderma. A previous study from the investigators' group found an elevated prevalence of AT1R-Ab in patients with lupus nephritis. ...

Phase N/A