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Pneumonia Clinical Trials

A listing of Pneumonia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (358) clinical trials

Hydroxychloroquin (HCQ) in Pediatric Interstitial Lung Disease (ILD)

This study is an explorative, prospective, randomized, double-blind, placebo controlled investigation of hydroxychloroquine (HCQ) in pediatric ILD. The treatments are organized in START and STOP blocks, which can be initiated in sequence, as needed by the subjects. Each patient can participate in each block only once. In the START block ...


Decreasing Antibiotic Use in Infants With Suspected Ventilator-associated Infection

In 2011 the Centers for Disease Control (CDC) estimated antibiotic-resistant infections resulted in $20 billion in excess healthcare costs and more than 100,000 unnecessary deaths in the U.S. alone. Ventilator-associated infections (VAI) are the most commonly diagnosed hospital-acquired infections in the pediatric intensive care unit (PICU) and account for more ...

Phase N/A

Blue Light Therapy in Reducing Inflammation During Sepsis

Background and preliminary data: Our murine studies suggest that exposure to blue (480nm) light, by comparison to ambient white or amber (580nm) light, reduces the inflammatory response (i.e., cytokine concentration), risk of organ failure (i.e., kidney failure), and improves the clearance and control of the infectious focus (i.e., reduced abdominal ...

Phase N/A

Invasive Pulmonary Aspergillosis Complicating Influenza Infection

This prospective multicentre case-control registration study in Dutch and Belgian ICUs will assess the difference in incidence and outcome of invasive pulmonary aspergillosis (IPA) in ICU patients with severe influenza compared with influenza-negative control patients with severe community-acquired pneumonia during the coming three influenza seasons (2017-2020). The study will further ...

Phase N/A

The Norwegian Antibiotics for Pneumonia in Children Study

The overall objective of the study is to determine if antibiotic therapy is beneficial in children with pneumonia who do not have a highly suspicious bacterial infection, such as in lobar pneumonia. Secondary objective is to determine whether antibiotic use influence the microbial flora, including antibiotic resistance, in the airways ...


PROcalcitonin Pneumonia / Pneumonitis Associated With ASPIration

There is actually no consensus in place defining for which patients with suspected inhalation pneumonia antibiotic treatment should be initiated and what the duration of this antibiotic treatment should be. This absence of recommendations results in excessive use of antibiotics, in emergence of multi-resistant strains and increase of costs. Several ...


PET Imaging CCR2 in Lung Inflammation

This is a single site, pilot Phase 0/1 clinical trial to establish initial estimates of the human radiation dosimetry of 64Cu-DOTA-ECL1i. Healthy volunteers and participants who currently smoke cigarettes but do not have known pulmonary disease will be recruited. Twelve participants (N=6 healthy, N=6 current smokers) will undergo whole-body PET/CT ...

Phase N/A

Adjunctive Therapy of Andrographolid Sulfonatein Community Acquired Pneumonia

Adjunctive Therapy of AndrographolidSulfonate in Community Acquired Pneumonia: A Multicenter, Randomized,Double-blinded, Placebo Controlled Clinical Trial. The hypothesis is that combination therapy with Andrographolid Sulfonatein injection and antibacterial is significantly better than antibacterial alone in achieving clinical stability among hospitalized CAP patients.


Children's Automated Respiration Monitor (ChARM) for Child Pneumonia Diagnosis by Community Health Workers in Mali

Methodology The study is designed as a community based, cluster randomized, pragmatic, intervention trial. It will be conducted within the existing 2016-2020 project structure. Specifically, the intervention will evaluate the potential of the ChARM device to improve CHWs competency in counting respiratory rate and diagnose pneumonia more accurately in children ...

Phase N/A

Diagnostic Breath Analysis for Detection of Ventilator Acquired Pneumonia (VAP)

On clinical suspicion of VAP, breath samples will be collected from the expiratory limb of the patient's ventilator tubing circuit. A sterile Tedlar collection bag will be used to connect to the sample port and collect the breath sample. The expiratory limb sample port will be utilized to ensure maintenance ...

Phase N/A