Depression Clinical Trials

A listing of Depression medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 153 clinical trials
Chinese Herbal Medicine and Micronized Progesterone for Live Births in Threatened Miscarriage

Threatened miscarriage is manifested by vaginal bleeding, with or without abdominal pain, while the cervix is closed and the fetus is viable and inside the uterine cavity. Threatened miscarriage is a common complication of pregnancy occurring in 20% of all clinically recognized pregnancies and about half of these will eventually …

early pregnancy
  • 39 views
  • 25 Jan, 2021
  • 10 locations
Open Label Multi-Site Study of Safety and Effects of MDMA-assisted Psychotherapy for Treatment of PTSD With Optional fMRI Sub-Study

This open-label, lead-in Phase 2 study is intended to gather supportive data on the safety and effectiveness of manualized MDMA-assisted psychotherapy as a treatment for PTSD. This will be the first study of MDMA-assisted psychotherapy in Europe using the CAPS-5 as a primary outcome measure to confirm assumptions made for …

suicidal
functional magnetic resonance imaging
psychotherapy
mdma
hypertension
  • 198 views
  • 01 Aug, 2021
  • 9 locations
Sacubitril/Valsartan vs Lifestyle in Hypertrophic Cardiomyopathy

The overall aim of this project is to establish potential benefits of a novel lifestyle (physical activity and dietary nitrate) and pharmacological (angiotensin receptor neprilysin inhibitor) interventions in patients with hypertrophic cardiomyopathy (HCM). HCM is the most common genetic cardiovascular disease with a broad spectrum of disease severity. Angiotensin receptor …

angiotensin
hypertrophy
neprilysin inhibitor
vasodilatation
heart failure
  • 0 views
  • 24 Jan, 2021
  • 5 locations
Salicylic Augmentation in Depression

The investigators are doing this research study to find out if using aspirin along with antidepressant treatment can lessen symptoms of depression. This study also aims to find out if some

depression
antidepressants
behavioral therapy
depressive symptoms
cognitive therapy
  • 18 views
  • 24 Jan, 2021
Scopolamine in Bipolar Depression

IV Scopolamine, compared to placebo, in reducing severity of depression in individuals with bipolar disorder who are experiencing a depressive episode of at least moderate severity

  • 0 views
  • 16 May, 2021
  • 1 location
Lipopolysaccharide (LPS) Challenge in Depression

LPS Challenge in Individuals with Major Depressive Disorder

depression
depressive symptoms
major depressive disorder
fluoxetine
depressed mood
  • 192 views
  • 24 Jan, 2021
  • 1 location
NMDA Modulation in Major Depressive Disorder

Most of the current antidepressants for major depressive disorder (MDD) are based upon the monoamine hypothesis which cannot fully explain the etiology of depression. NMDA hypofunction has been

  • 0 views
  • 26 Jan, 2021
  • 1 location
5-HTP and Creatine for Depression

This is a three-armed clinical trial examining the effect of 5-hydroxytryptophan and creatine monohydrate as augmenting agents for the treatment of depression. Subjects will be randomized

  • 0 views
  • 11 May, 2021
  • 1 location
Dopaminergic Dysfunction in Late-Life Depression

carbidopa/levodopa (L-DOPA) will improve depressive symptoms.

  • 0 views
  • 24 Feb, 2021
  • 1 location
Ketamine Alcohol (in Treatment-Resistant Depression)

depressive disorder (TRD). A family history of an alcohol use disorder (Family History Positive, FHP) is one of the strongest identified predictors of an improved antidepressant response to ketamine. Like

depression
antidepressants
major depressive disorder, single episode
ketamine
major depressive disorder
  • 57 views
  • 25 Jan, 2021
  • 2 locations