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Esophageal Cancer Clinical Trials

A listing of Esophageal Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (9) clinical trials

Evaluation of Ocoxin -Viusid in Advanced Stomach Cancer and Gastric Esophagogastric Junction

To evaluate the effect of Ocoxin-Viusid on the quality of life of patients To evaluate the toxicity of Ocoxin-Viusid in combination with chemotherapy (QT). To assess the influence of Ocoxin-Viusid on tolerance to treatment with chemotherapy. Identify the changes that occur in the nutritional status of patients receiving the supplement.


EMST and Swallowing in Long-Term Survivors of HNCA

Twenty (20) persons treated for cancer of the head and neck (HNCA) with radiation therapy or chemoradiotherapy (RT/CRT) at least 5 years previously will be randomized to an 8-week program of either EMST only and Standard Care only in order to examine the impact of EMST on swallowing function. The ...

Phase N/A

Prehabilitation in Esophageal Surgery (PRESS)

Multi-modal prehabilitation programs reported positive results in patients undergoing colonic resection. These protocols are, generally, based on physiotherapist, nutritional and psychological implementation programs. Nevertheless, the conflicting results obtained in previous trials demonstrate how many elements have still to be clarified and that, probably, the pre-habilitation interventions must be tailored, as ...

Phase N/A

Safety and Efficacy of IMC-C103C as Monotherapy and in Combination With Atezolizumab

The IMC-C103C-101 Phase 1/2 study will be evaluated in patients with metastatic/unresectable tumors of interest which include NSCLC, esophageal carcinoma, gastric carcinoma, HNSCC, and urothelial carcinoma and will be conducted in two phases. A Phase 1 dose escalation study to identify the MTD/RP2D of IMC-C103C as monotherapy (Arm A1) and ...


Cardiopulmonary Toxicity of Thoracic Radiotherapy

In the present study, the incidence and time course of treatment-related changes in cardio-pulmonary physiology will be assessed using standard diagnostic tools such as echocardiography, cardiac MRI (CMR) and serum biomarkers and relate them to the radiation dose distribution. Such insight in the characteristics of this possible radiation-induced PH and ...

Phase N/A

Safety and Efficacy of KY1044 and Atezolizumab in Advanced Cancer

A Phase 1/2, open label, multi-center study to evaluate the safety, efficacy and tolerability of KY1044 as single agent and in combination with anti-PD-L1 (atezolizumab) in adult patients with selected advanced malignancies, who are ineligible for or there are no available therapies known to confer a clinical benefit for their ...


Distribution of Lymph Node Metastases in Esophageal Carcinoma

Primary Objective: Aim of the TIGER study is to evaluate the distribution of lymph node metastases in esophageal carcinoma specimens following transthoracic esophagectomy with at least 2-field lymphadenectomy. Secondary Objective(s): Accuracy of preoperative diagnostics (especially EUS and PET-CT) and added value of EBUS (endobronchial ultrasonography) to existing staging with EUS ...

Phase N/A

Oesophagectomy and Chest Wall and Respiratory Function

The study population consists of 50 healthy volunteers who have not received upper gastrointestinal surgery and 100 patients treated with surgery more than one year ago (50 open and 50 minimally invasive). Chest wall movement will be measured using a 3D optical motion system and the investigators will establish if ...

Phase N/A

Pilot Immunotherapy Study With Autologous T-cells Specific for New York Esophageal Antigen-1 (NY-ESO-1)/ Cancer-testis Antigen-2 (LAGE-1a)-Positive Advanced Non-small Cell Lung Cancer (NSCLC) Either Alone or in Combination With Pembrolizumab

Adoptive T-cell therapy (ACT) is a therapeutic approach that uses T lymphocytes of subjects with cancer, obtained by leukapheresis with the aim of generating an anti-tumor T-cell immune response. NY-ESO-1 and LAGE-1a antigens are tumor-associated proteins that have been found in several tumor types. Clinical trials using ACT with T-cells ...