Head and Neck Cancer Clinical Trials

A listing of Head and Neck Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 101 clinical trials
CAB-ROR2-ADC Safety and Efficacy Study in Patients With TNBC or Head & Neck Cancer (Ph1) and NSCLC or Melanoma (Ph2)

The objective of this study is to assess safety and efficacy of CAB-ROR2-ADC in solid tumors

renal function test
solid tumour
triple negative breast cancer
lung carcinoma
  • 19 Sep, 2021
  • 11 locations
Testing the Addition of M3814 (Peposertib) to Radiation Therapy for Patients With Advanced Head and Neck Cancer Who Cannot Take Cisplatin

This phase I trial investigates the side effects and best dose of peposertib when given together with radiation therapy in treating patients with head and neck cancer that has spread to other

  • 22 Sep, 2021
  • 9 locations
Mouth Opening Prevention Education Nutrition (OPEN)

In France, 11 316 new cases of upper aero-digestive tract cancer were estimated in 2012. These cancers are treated with a triple-therapy combining surgery, radiotherapy and chemotherapy/targeted therapies. Treatment-induced sequelae are often burdensome: reduction in mouth opening, eventually on to trismus, limitation of lips and tongue mobility, deterioration in oral …

dental caries
squamous cell carcinoma
  • 12 Sep, 2021
  • 7 locations
Effects of Preoperative Enteral Immunonutrition for Esophageal Cancer Patients Given Neoadjuvant Chemoradiotherapy

This randomized controlled trial will evaluate the effects of preoperative enteral immunonutrition in esophageal cancer patients undergoing neoadjuvant therapy. The purpose of this study is to determine whether preoperative immune-modulating diet before surgery can improve the rate of complications and other perioperative outcomes.

esophagus cancer
  • 12 Sep, 2021
  • 5 locations
Study of PDS0101 and Pembrolizumab Combination I/O in Subjects With HPV16 + Recurrent and/or Metastatic HNSCC

VERSATILE-002 is a Phase 2, open-label, multicenter study of the efficacy and safety of PDS0101 administered in combination with pembrolizumab in the first line treatment of adults with HPV16 and PD-L1 positive recurrent or metastatic head and neck squamous cell carcinoma (HNSCC).

squamous cell carcinoma
conjugated bilirubin
neutrophil count
  • 26 Sep, 2021
  • 15 locations
A Study Using Regorafenib as Second or Third Line Therapy in Metastatic Medullary Thyroid Cancer

This research study is studying a targeted therapy as a possible treatment for thyroid cancer. A targeted therapy is a type of treatment that uses drugs or other substances to identify and attack specific types of cancer cells with less harm to normal cells. The name of the study intervention …

medullary thyroid carcinoma
neutrophil count
platelet count
renal function
  • 23 Sep, 2021
  • 2 locations
Nivolumab for the Reversal of Squamous Dysplasia in High Risk Current and Former Smokers

that are at high risk for the development of lung cancer, including those with a prior smoking history, or history of lung cancer or head and neck cancer. The safety and tolerability of nivolumab will

  • 17 Sep, 2021
  • 2 locations
Radiofrequency Ablation of Low Risk Papillary Thyroid Microcarcinoma

This is a single center prospective clinical trial with regard to efficacy and safety of radiofrequency ablation of papillary thyroid microcarcinoma.

fine needle aspiration
  • 26 Sep, 2021
  • 1 location
A Study Evaluating Different Doses of BI 765049 When Given Alone and When Given With BI 754091 to Patients With Advanced Solid Tumors Having the B7-H6 Marker

This study is open to adults with advanced solid tumors whose previous cancer treatment was not successful. People can participate if their tumor has the B7-H6 marker or if they have colorectal cancer. The study tests 2 medicines called BI 765049 and BI 754091. Both medicines may help the immune …

  • 16 Sep, 2021
  • 3 locations
  • 18 Sep, 2021
  • 12 locations