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Head and Neck Cancer Clinical Trials

A listing of Head and Neck Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (9) clinical trials

Study of MEDI0562 Prior to Surgical Resection in Head and Neck Squamous Cell Carcinoma (HNSCC) or Melanoma

This clinical trial is the first to evaluate the safety and feasibility of a humanized OX40 agonist, MEDI0562, in the pre-operative setting for patients with head and neck squamous cell carcinoma or melanoma. Patients will be randomly assigned to one of two MEDI0562 administration schedules; initially 5 patients will enroll ...

Phase

PaRTNer: Patient Reported Outcomes and Financial Toxicity in Head and Neck Cancer A Pilot Survey Based Study

This is a prospective, single institution, survey-based study to assess OOP costs, financial toxicity and pateint reported outcomes (PROs') (including QOL, quality of care, and attitudes/perspectives on the role of cost in treatment decisions). Potential participants are new patient consults in Radiation Oncology Head and Neck Cancer Clinic. Patients with ...

Phase N/A

Manual Therapy in Treating Fibrosis-Related Late Effect Dysphagia in Head and Neck Cancer Survivors

PRIMARY OBJECTIVES: I. To determine the feasibility and safety of manual therapy for treatment of fibrosis-related dysphagia in head and neck cancer survivors. SECONDARY OBJECTIVES: I. To examine preliminary efficacy, dose-response (number of treatment sessions to normalized cervical range of motion), and durability of manual therapy for improving cervical range ...

Phase N/A

Early Detection of Tumors of the Digestive Tract by Confocal Endomicroscopy

Confocal Endomicroscopy procedure: eligible patients which consent to participate in the study will be submitted to endoscopic procedures under conscious or deep sedation. The patients will receive an intravenous injection of 2.5-5 mL of 10% sodium fluorescein at the beginning of the endoscopic procedure. The endoscope will target the area ...

Phase N/A

EACH: Evaluating Avelumab in Combination With Cetuximab in Head and Neck Cancer

This is a randomised phase II study comparing the efficacy of avelumab alone with avelumab + cetuximab combination in patients with platinum-resistant advanced or metastatic head & neck cancer. The randomised phase II part of the trial will be preceded by a safety run-in.The objective of the safety run in ...

Phase

Follow up for Patients With Thyroid Cancer Planed for Radioiodine Scan or Treatment

Objective To observe the difference between Thyogen injection or Eltroxin withdrawal on metabolic profile. Background and method: The prevalence of thyroid cancer has increased in recent decades. Patients with thyroid cancer need to choose between Thyrogen injection and Eltroxin withdrawal before radioiodine therapy or scan. This is a prospective, observational ...

Phase N/A

A Phase 1b Dose Escalation/Expansion Study of Abexinostat in Combination With Pembrolizumab in Patients With Advanced Solid Tumor Malignancies

PRIMARY OBJECTIVES: I. To determine the maximally tolerated and recommended phase 2 dose of abexinostat in combination with anti-PD-1/PD-L1 checkpoint inhibitor (CPI). (Dose escalation) II. To determine the objective response rate (ORR) by Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 criteria in patients treated with abexinostat in combination with ...

Phase

Effect of Three Different Peak Airway Pressures on Determining Intraoperative Bleeding in Thryroidectomies

Patients will be divided into three groups (https://www.randomizer.org/) by computer assisted randomization method (30 cm H2O in Group I, 40 cm H2O in Group II, 50 cmH2O in Group III peak pressure will be applied). The time until the first hemorrhage is seen in each group or if not seen ...

Phase N/A