Amyotrophic Lateral Sclerosis (ALS) Clinical Trials

A listing of Amyotrophic Lateral Sclerosis (ALS) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 129 clinical trials
A Study of BIIB067 When Initiated in Clinically Presymptomatic Adults With a Confirmed Superoxide Dismutase 1 Mutation

initiated prior to versus at the time of emergence of clinically manifest amyotrophic lateral sclerosis (ALS).

  • 0 views
  • 16 Sep, 2021
  • 32 locations
Olanzapine for the Treatment of Appetite Loss in Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis (ALS) is an adult neurodegenerative disease that is caused by a selective degeneration of the motor nerve cells in the cortex and myelon. As a result of

primary lateral sclerosis
riluzole
atrophy
neurodegenerative disorders
  • 42 views
  • 07 Nov, 2020
  • 1 location
Cistanche Total Glycosides for Amyotrophic Lateral Sclerosis: A Randomized Control Trial (RCT) Study Assessing Clinical Response

This study will examine the effectiveness of Cistanche Total Glycosides(CTG) in treating patients with amyotrophic lateral sclerosis (ALS) - a fatal neurological degenerative disease that

spinal cord
weakness
spinal cord diseases
respiratory failure
riluzole
  • 30 views
  • 07 Nov, 2020
  • 1 location
Safety Extension Study of Oral Edaravone Administered in Subjects With Amyotrophic Lateral Sclerosis (ALS)

in subjects with Amyotrophic Lateral Sclerosis (ALS) for up to 96 weeks.

edaravone
primary lateral sclerosis
  • 0 views
  • 22 Sep, 2021
  • 48 locations
MERIDIAN: A Study to Evaluate the Efficacy and Safety of Pegcetacoplan in Adults With Amyotrophic Lateral Sclerosis (ALS)

This is a 24-month, Phase 2, multicenter, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of pegcetacoplan in subjects with amyotrophic lateral sclerosis

primary lateral sclerosis
  • 17 views
  • 19 Aug, 2021
  • 30 locations
A Study to Evaluate the Efficacy and Safety of Reldesemtiv in Patients With Amyotrophic Lateral Sclerosis (ALS)

The purpose of this study is to assess the effect of reldesemtiv versus placebo on functional outcomes in ALS.

riluzole
weakness
primary lateral sclerosis
edaravone
  • 0 views
  • 24 Sep, 2021
  • 12 locations
Motor Neurone Disease - Systematic Multi-Arm Adaptive Randomised Trial

MND-SMART is investigating whether selected drugs can slow down the progression of motor neurone disease (MND) and improve survival. The study is 'multi-arm' meaning more than one treatment will be tested at the same time. In the first instance the trial will have 3 arms; drug 1, drug 2 and …

memantine
motor neuron disease
primary lateral sclerosis
atrophy
progressive muscular atrophy
  • 8 views
  • 03 Jul, 2021
  • 8 locations
Safety and Efficacy of TUDCA as add-on Treatment in Patients Affected by ALS

Patients Affected by Amyotrophic Lateral Sclerosis (ALS).

pulmonary function test
riluzole
dysphagia
primary lateral sclerosis
  • 139 views
  • 28 Mar, 2021
  • 33 locations
Efficacy and Safety Study of Oral Edaravone Administered in Subjects With ALS

To evaluate and compare the efficacy of two dosing regimens of oral edaravone in subjects with amyotrophic lateral sclerosis (ALS) based on the change in ALS Functional Rating ScaleRevised

edaravone
primary lateral sclerosis
  • 0 views
  • 24 Sep, 2021
  • 57 locations
HEALEY ALS Platform Trial - Master Protocol

The HEALEY ALS Platform Trial is a perpetual multi-center, multi-regimen clinical trial evaluating the safety and efficacy of investigational products for the treatment of ALS.

riluzole
weakness
treatment regimen
edaravone
  • 144 views
  • 05 Sep, 2021
  • 51 locations