Amyotrophic Lateral Sclerosis (ALS) Clinical Trials

A listing of Amyotrophic Lateral Sclerosis (ALS) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 117 clinical trials
Olanzapine for the Treatment of Appetite Loss in Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis (ALS) is an adult neurodegenerative disease that is caused by a selective degeneration of the motor nerve cells in the cortex and myelon. As a result of

primary lateral sclerosis
atrophy
riluzole
neurodegenerative disorders
  • 40 views
  • 07 Nov, 2020
  • 1 location
Cistanche Total Glycosides for Amyotrophic Lateral Sclerosis: A Randomized Control Trial (RCT) Study Assessing Clinical Response

This study will examine the effectiveness of Cistanche Total Glycosides(CTG) in treating patients with amyotrophic lateral sclerosis (ALS) - a fatal neurological degenerative disease that

primary lateral sclerosis
respiratory failure
weakness
degenerative disorder
riluzole
  • 30 views
  • 07 Nov, 2020
  • 1 location
Variability of the Unique Fiber Potentials of a Spastic Muscle Treated With Botulinum Toxin

The main objective is to study the variability and evolution of single-fiber jitter and fiber density (FD) electrophysiological parameters in a spastic muscle during botulinum toxin type A (BTA) treatment in hemiplegic patients after stroke, according to primary or multi-injected status. The secondary objectives of this study are: To establish …

  • 0 views
  • 04 Apr, 2021
  • 1 location
Motor Neurone Disease - Systematic Multi-Arm Adaptive Randomised Trial

MND-SMART is investigating whether selected drugs can slow down the progression of motor neurone disease (MND) and improve survival. The study is 'multi-arm' meaning more than one treatment will be tested at the same time. In the first instance the trial will have 3 arms; drug 1, drug 2 and …

progressive muscular atrophy
memantine
primary lateral sclerosis
neurodegenerative disorders
atrophy
  • 8 views
  • 24 Jan, 2021
  • 1 location
Efficacy and Safety Study of Oral Edaravone Administered in Subjects With ALS

To evaluate and compare the efficacy of two dosing regimens of oral edaravone in subjects with amyotrophic lateral sclerosis (ALS) based on the change in ALS Functional Rating ScaleRevised

edaravone
primary lateral sclerosis
  • 0 views
  • 16 Jun, 2021
  • 39 locations
Safety and Efficacy of TUDCA as add-on Treatment in Patients Affected by ALS

Patients Affected by Amyotrophic Lateral Sclerosis (ALS).

pulmonary function test
dysphagia
riluzole
primary lateral sclerosis
  • 134 views
  • 28 Mar, 2021
  • 33 locations
HEALEY ALS Platform Trial - Master Protocol

The HEALEY ALS Platform Trial is a perpetual multi-center, multi-regimen clinical trial evaluating the safety and efficacy of investigational products for the treatment of ALS.

weakness
edaravone
riluzole
treatment regimen
  • 144 views
  • 12 Jun, 2021
  • 51 locations
RT001 in Amyotrophic Lateral Sclerosis

RT001-014 is a Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study to Assess Efficacy, Long Term Safety and Tolerability of RT001 in Subjects with Amyotrophic Lateral Sclerosis

  • 0 views
  • 17 Jun, 2021
  • 4 locations
Outcomes Mandate National Integration With Cannabis as Medicine for Prevention and Treatment of COVID-19

This will be a multistate, multicenter clinical study to determine the efficacy and safety of medical cannabis for a wide variety of chronic medical conditions.

covid-19
disease or disorder
brimonidine tartrate ophthalmic solution
medical marijuana
  • 12450 views
  • 27 Jan, 2021
  • 16 locations
Enoxacin for Amyotrophic Lateral Sclerosis (ALS)

The study will assess the safety of the drug enoxacin at specific dose levels in adults with ALS.

edaravone
primary lateral sclerosis
riluzole
  • 0 views
  • 26 May, 2021
  • 1 location