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Asthma Clinical Trials

A listing of Asthma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found (318) clinical trials

Feasibility and Acceptability of the Propeller Monitoring System in Children With Persistent Asthma

This study is a prospective cohort study using a pre-/post-design. The target population consists of children and adolescents 10-18 years old making an ED visit or admitted to the hospital at Connecticut Children's Medical Center for an asthma exacerbation. All patients will receive two Hailie devices (for controller and rescue …

Phase N/A

Change of NLRP3 Inflammasome Expression Level Symptoms and Functional Status in HFpEF Patients Treated With ARNI

The study will integrate data from two trials involving a total of 90 participants with heart failure. Depending on the using of ARNI, participants in HFpEF group will be divided into two groups. The diagnostic criteria for HFpEF is: (1) left ventricular ejection fraction 50% (2with the symptoms and/or signs …

Phase N/A

Predicting Intubation of Patients Hospitalised for Acutely Attacked Asthma

Although the asthmatic treatments currently be effective in term of efficacy of inhaled medications and good clinical outcome including symptom controlled and asthma exacerbation number, the large number of worse event still have been reported. Few cases eventually have been intubated and died even though using optimal medication. In this …

Phase N/A

The Development of a Screening Assay by LC-MS/MS to Monitor Adherence to Asthma Treatment

Phase I: laboratory based study to develop LC-MS/MS assay of urine / blood to detect presence or lack asthma medication in 50 volunteers with asthma. Phase II: once the test is validated it will be tested in a 100 patients attending the asthma clinics to test its clinical utility. Urine …

Phase N/A

Heart Failure and Aortic Stenosis Transcriptome

The investigators will collect plasma and cardiac tissue specimens from consenting subjects. The investigators will evaluate the expression of mRNAs, miRNAs and lncRNAs in patients affected by both end-stage and not end-stage HF as well as in patients affected by aortic stenosis and undergoing valve replacement and requiring cardiac myectomy. …

Phase N/A

Cancer Therapy Effects on the Heart

Anthracycline chemotherapies (e.g. doxorubicin, daunorubicin) is commonly given to treat pediatric cancer, and carries a risk of cardiotoxicity. Over the long term, children who receive these therapies have an increased risk of heart failure and early cardiovascular death. However, current strategies for identifying patients who are at risk prior to …

Phase N/A

Towards Targeting the ORigin of the Inflammatory Cascade in Allergic Asthma

Allergic asthma is a complex and heterogeneous disease caused by excessive responses to inhaled allergens. Current medication, including corticosteroids and bronchodilators, does not act on the origin of inflammation but rather combats symptoms, leaving many patients uncontrolled. Airway epithelium is critical for the initiation and progression of asthma pathology. We …

Phase N/A

Sensing Ventricular Arrhythmias by His Bundle Leads

During routine testing of implanted leads, the His bundle lead will be connected to a separate device with all therapies disabled. Testing will be done to see if the His bundle lead can detect ventricular arrhythmias.

Phase N/A

Predictive Models of Readmission in Heart Failure

Objective: To create models for predicting the risk of readmission short term (30-90 days) and medium term (one year).To identify differences between patients readmitted and not readmitted, and profiles of frequently preventable readmissions in our setting. Methodology: Observational prospective cohort of patients who are discharged with a diagnosis of heart …

Phase N/A

EMPOWER-1: A Multi-site Clinical Cohort Research Study to Reduce Health Inequality

This multi-centre real-world study will recruit patients across different National Health Service (NHS) sites based in England, where the overall patient population demographic profile is sufficiently variable to allow for meaningful representation of different ethnicities in the analysis of pooled data-sets. The study addresses the issue of health inequality and …

Phase N/A