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Asthma Clinical Trials

A listing of Asthma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (91) clinical trials

Characterization of Adults for Asthma Microbiome Research Studies

This is a prospective, observational, two-visit study in which approximately 200 subjects will be enrolled, including healthy controls, atopic controls without asthma, and patients with stable asthma (n = 150). Among asthmatics, 2/3 will be on regular inhaled corticosteroid therapy and 1/3 will not be taking inhaled corticosteroids. Subjects who ...

Phase N/A

NHALES (Natural History of Asthma With Longitudinal Environmental Sampling)

This study will be a prospective, longitudinal, observational, single-center, exploratory, natural history study to collect samples and data that will enable prospective explorations of the interaction between environmental exposures and disease progression over time in moderate-severe atopic asthmatics with persistent disease, and facilitate the formation of mechanistic hypotheses. Environmental and ...

Phase N/A

Adult Arm of DZL All Age Asthma Cohort (ALLIANCE)

The clinical heterogeneity of asthma patients has been increasingly recognised within the last years. Recent studies and articles highlighted the idea of asthma not beeing a single disease but rather a unifying term for multiple phenotypes. Phenotype in this sense is defined as the combination of observable properties of an ...

Phase N/A

A Prospective Observational Study of Biopredictors of Bronchial Thermoplasty Response in Patients With Severe Refractory Asthma (BTR Study)

Primary Aim To assess the relationship between baseline clinical, physiologic, biologic and imaging markers and response to bronchial thermoplasty, defined by improvement in asthma quality of life, in patients with severe refractory asthma. Secondary Aims To assess the relationship between baseline clinical, physiologic, biologic and imaging markers and response to ...

Phase N/A

BIOmarkers in Severe AsthMa Patients on Omalizumab Treatment

Anti-IgE (omalizumab) has been shown to be an effective add-on therapy for patients with allergic severe asthma. In this observational study patients aged over 18 year with uncontrolled severe persistent asthma are selected for add-on therapy with omalizumab. Patients were on high dose of ICS and had a documented history ...

Phase N/A

The Genetics of Severe Asthma in Children

Our primary outcome measure is the development of a near fatal asthma exacerbation. Secondary outcome measures will include the duration of continuously nebulized ADR2 agonist therapy and the duration of IV ADR2 agonist therapy. Children will be stratified by ADR2 genotype at amino acid position 16 and outcomes compared. We ...

Phase N/A

Genetics of the Early and Late Response to Allergen Challenge

Asthmatic and/or allergic rhinitis ('hay fever') individuals respond differently, but reproducibly, to allergen challenge. Some individuals develop an isolated early response while others also go on to develop a late response. In asthmatic individuals, airway narrowing represents the early phase of the asthmatic response to airway challenge; early phase onset ...

Phase N/A

Longitudinal Observational Study in Prematurely Born Preschool Children: Assessment of Lung Function Parameters

The PRE-AR project is a longitudinal observational study. The primary objective is the assessment of lung function parameters in late preterm preschool children. Pulmonary function tests will be performed.

Phase N/A

Vaccination Responses in Young and Older Adults

The primary investigation involves integrative multi-omics monitoring of individuals following their pneumonia vaccination over twelve time points. Genomic sequencing will be used to evaluate the volunteer's genomic risks based on variants with known disease association. Full transcriptome (via RNA-Sequencing), proteome and metabolome profiling (via mass spectrometry) will be performed per ...

Phase N/A

Registry for Asthma Characterization and Recruitment 2

The overall goal of the Registry for Asthma Characterization and Recruitment 2 (RACR2) is to create a database of participants who are potentially eligible for future Inner City Asthma Consortium (ICAC) clinical research studies. The registry will provide an avenue to assess various asthma and allergy characteristics, which will result ...

Phase N/A