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Asthma Clinical Trials

A listing of Asthma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (141) clinical trials

Nasal Tracheal and Bronchial Mucosal Lining Fluid(MLF) Sampling From Patients With Respiratory Diseases

Aim- To define the diagnosis, stratification and monitoring of IPF, sarcoidosis and TB, providing targets and biomarkers for new therapy. The investigators will study asthma and COPD patients with inflammation of the airways, and to compare with healthy control subjects. Characterising inflammation using upper airway sampling may eventually remove the ...

Phase N/A

Site and Mechanism(s) of Expiratory Airflow Limitation in COPD Emphysema and Asthma-COPD Overlap

The investigators are interested in determining the predominant site of expiratory airflow limitation including large central airways vs small peripheral airways/alveoli. In mild to moderate obstructive airways disease and emphysema, I believe routine spirometry including FEV 1(L), FVC (L), and FEV 1/FVC % may be normal, despite expiratory airflow limitation ...

Phase N/A

MCT and Capsaicin Provocation Challenge in Diagnosis of Chronic Cough

The present study has the following objectives: to assess the prevalence of BHR in non-smoking adults with a chronic cough, to assess the prevalence of BHR in patients with UACS and GERD, to evaluate the relationship between BHR and cough reflex sensitivity, to assess the diagnostic accuracy of MCT in ...

Phase N/A

EXhaled Hydrogen Peroxide As a Marker of Lung diseasE (EXHALE) Pilot Study.

Hydrogen Peroxide levels in Exhaled Breath Condensate (EBC) is a direct biomarker of oxidative stress from the airway epithelium. Levels have been shown to be raised in asthma and Chronic Obstructive Pulmonary Disease (COPD) both in stable and exacerbating states. Previously it has been difficult to measure this volatile compound ...

Phase N/A

The Application of Impulse Oscillometry on the Diagnosis of ACOS Asthma and COPD.

ACOS,asthma and COPD are prevalent diseases with similar manifestations and different type airway impairments. The differential diagnosis is not easy because the patients always complain of the similar symptoms and are not able to complete spirometry well. Impulse Oscillometry System (IOS) is capable of identifying airway obstruction and reactions to ...

Phase N/A

Clinical Characteristics Treatment and Prognosis of Chest Tightness Variant Asthma

Asthma, abbreviation for bronchial asthma, is one of the common chronic airways disease that threatens human health. Typical symptoms of asthma are recurrent wheezing, shortness of breath, chest tightness and cough, usually occurring at night or early morning. However, there are still some patients with only persistent clinical manifestations of ...

Phase N/A

Evaluation of the Effectiveness and Quality of Life With the Administration of the Fixed Combination of Budesonide Formoterol in Greek Patients With Asthma During Routine Clinical Practice.

Asthma is a heterogeneous disease, usually characterized by chronic inflammation of the airways. Characterized by a history of respiratory symptoms such as wheezing, chest heaviness and cough symptoms that fluctuate over time, as well as variable airway obstruction. Asthma is a common disease worldwide, the rates of which are increasing ...

Phase N/A

Identifying Patients With the COPD-Asthma Overlap Phenotype: Therapeutic Implications

Background: Asthma and COPD are considered different diseases but many patients share characteristics of both entities. This has been termed "COPD-asthma overlap syndrome". Study objective: To examine: (a) the frequency of the overlap phenotype among patients referred for pulmonary function testing and, (b) the impact of this phenotype on the ...

Phase N/A

Study of the Frequency and of the Regulatory Function of Positive T Lymphocytes Dual CD4CD8aa (DP8a) Specific to a Bacteria of the Intestinal Microbiota (Faecalibacterium Prausnitzii) in Atopic Dermatitis Asthma and Allergic Rhinitis

The primary endpoint will be the highlight of a quantitative reduction of double positive T cells (CD4 + / CD8 +) the specific F prausnitzii peripheral blood in patients with allergic asthma, allergic rhinitis and atopic dermatitis compared to samples from a control sample collection made available by the laboratory ...

Phase N/A

Identification of Asthma Phenotypes in Severe Asthmatics

Asthma is a heterogeneous disorder presenting with many phenotypes. Most asthmatics have mild to moderate disease. However, 5-20% of asthmatics belong to the "Difficult-to-treat" or more severe group and they account for 50-80% of asthma health care costs. In a tertiary hospital like Singapore General Hospital, most of our asthmatics ...

Phase N/A