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Asthma Clinical Trials

A listing of Asthma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (467) clinical trials

Registry for Asthma Characterization and Recruitment 2

The overall goal of the Registry for Asthma Characterization and Recruitment 2 (RACR2) is to create a database of participants who are potentially eligible for future Inner City Asthma Consortium (ICAC) clinical research studies. The registry will provide an avenue to assess various asthma and allergy characteristics, which will result ...

Phase N/A

School Inner-City Asthma Intervention Study (SICAS-2)

Our proposal builds upon our established, successful school-based infrastructure to determine whether a school/classroom intervention will efficiently and effectively improve asthma morbidity by reducing these exposures. Our goal is to determine the efficacy of school/classroom based environmental intervention in reducing asthma morbidity in urban schoolchildren. Our central hypothesis is that ...

Phase N/A

AIRWEIGHS: Investigating Obesity as a Susceptibility Factor for Air Pollution in Childhood Asthma

The primary object of this study is to determine the efficacy of a targeted environmental intervention among overweight inner city children as compared to normal weight inner city children with asthma. Specific Aim #1: To determine if overweight inner-city children, compared to lean inner-city children, have greater improvement in asthma ...

Phase N/A

Sputum-derived Cellular Targets After Xolair (Omalizumab)

This is a randomized, placebo-controlled, double blind, 16-week intervention study to show feasibility and proof of concept. Analysis of whole induced sputum is under development for endotyping for asthma, allowing sampling of rare cells from conducting airways, repeated sampling, and cell-specific detailed genomic evaluation. Investigators have developed a novel technique ...

Phase

Ultra-long Acting Bronchodilator Therapy in Smoking Asthmatics

Cigarette smoking in asthma is associated with poorer asthma control and a higher frequency of asthma attacks. Despite this, smoking cessation rates are very low due to the highly addictive nature of tobacco smoking. Asthma in smokers is particularly challenging to manage because it is resistant to the beneficial effects ...

Phase

VCSIP Follow-up Study

The overall aims of this protocol are to determine whether prenatal supplementation with vitamin C to pregnant smokers can improve pulmonary function and decrease wheeze at 5 years of age in their offspring. This is a continuation of the VCSIP trial, to follow the offspring through 5 years of age. ...

Phase N/A

AsthMatic Inflammation and Neurocircuitry Activation (MINA)

Asthma is characterized by airway inflammation, bronchial hyperresponsiveness and airflow obstruction. The development of symptoms in patients with asthma is initiated by exposure to a variety of airborne substances including aeroallergens. The inhalation of these allergens by asthmatic subjects initiates a series of complex, interactive immune events through activation of ...

Phase N/A

PEEP as Rescue Therapy for Asthmatics With Elevated BMI

This study will investigate whether PEEP can prevent and/or reverse bronchoconstriction in asthmatics with a BMI > 35 kg/m2. People with late-onset non-allergic asthma that develops in the setting of obesity do not respond well to conventional asthma medications, likely because all treatments for asthma have been developed to treat ...

Phase

Indoor Air Pollution and Children With Asthma: An Intervention Trial

We have designed a randomized, double-blind, triple cross-over intervention study to examine the efficacy of indoor NO2 reduction on reducing asthma severity. Since particles and NO2 are both byproducts of combustion and associated with gas stove use, the intervention protocol includes a condition using a filter designed to remove particles ...

Phase N/A

Validation of the Hospital Asthma Severity Score (HASS)

Children aged 7-18 years will have a HASS score obtained by a single provider. After scoring is complete, a pulmonary technician will perform the spirometry test. Children aged 2 to 6 years old will concurrently (but separately) have their asthma severity graded by 2 individual measurers using the HASS tool ...

Phase N/A