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Ulcerative Colitis Clinical Trials

A listing of Ulcerative Colitis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (45) clinical trials

This study comprises three sub-studies. The objective of sub-study 1 is to characterize the dose-response, efficacy, and safety of ABT-494 compared to placebo in inducing clinical remission in order to identify the induction dose of ABT-494 for further evaluation in sub-study 2. The objective of sub-study 2 is to evaluate ...

Phase

A Phase 2, randomized, placebo-controlled, multi-center study to investigate the efficacy and safety of Apremilast (CC-10004) for the treatment of subjects with active ulcerative colitis

Phase

This study is designed to evaluate the effect of treatment with filgotinib on testicular safety in adult males with moderately to severely active Ulcerative Colitis (UC). Stipend range: $75o/v, $100proc For those patients who complete the trial, they will be eligible for the long-term extension study, for up to 195 ...

Phase

This is a phase 2a, randomized, double-blind, placebo-controlled, parallel group, multicenter study in subjects with active UC and a non-remission response to infliximab.   There will be up to 13 study visits, across the 12 weeks of treatment, along with 2 follow-up visits, at Weeks 16 and 22. Ideal patients ...

Phase

The primary objective of this study is to evaluate the testicular safety of filgotinib in adult males with moderately to severely active ulcerative colitis.

Phase

To demonstrate the efficacy of study drug, SER-287, to induce clinical remission in patients with active mild-to-moderate ulcerative colitis.  

Phase

This Phase 2 study is designed to evaluate the efficacy and safety of itacitinib in men and women with moderate to severe UC. The study consists of Part A and Part B, which consist of 12 weeks of double-blind, randomized, placebo-controlled treatment periods followed by 40 weeks open label extension ...

Phase

Phase 2 Dose-finding IMU-838 for Ulcerative Colitis

The investigational medicinal product (IMP) IMU-838 (vidofludimus calcium) is a new compound that selectively inhibits the human enzyme dihydroorotate dehydrogenase (DHODH). Dihydroorotate dehydrogenase plays a major role in the de-novo pyrimidine synthesis and is specifically expressed at high levels in proliferating or activated lymphocytes. Resting lymphocytes satisfy their pyrimidine requirements ...

Phase

Trial of Antimicrobials Versus Placebo in Addition to Fecal Transplant Therapy in Ulcerative Colitis

Patients aged 18 or over with active UC defined as a Mayo score > 3 with an endoscopic score >0 will be eligible for the study. Subjects will be excluded if they are participating in another clinical trial, are unable to give informed consent, have severe comorbid medical illness, have ...

Phase

Faecal Bacteriotherapy for Ulcerative Colitis

The etiopathogenesis of ulcerative colitis (UC) is not fully understood. One of the theories of UC pathogenesis represents a pathological response of mucosal immunity to intestinal microbiota. Potential therapeutic procedure how to affect this fact is the faecal microbiota transplantation (FMT). Review of the literature on FMT suggests great potential ...

Phase