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Ulcerative Colitis Clinical Trials

A listing of Ulcerative Colitis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (277) clinical trials

People with ulcerative colitis or Crohn's Disease are asked to participate in a research study being conducted by Montefiore Medical Center.  

Phase N/A

A trial for patients with moderate to severe Ulcerative Colitis. It is for those over 18 years of age that have experienced an inadequate response to, loss of response to, or are intolerant to conventional medications for the treatment of UC.

Phase N/A

Purpose of Study: The purpose of this study is to evaluate the safety and efficacy of different doses of upadacitinib and determine how well it works, as well as the pharmacokinetics (PK) (how drug is absorbed, distributed, and eliminated in the body over time) of upadacitinib in subjects with moderate ...

Phase

The purpose of this study is to evaluate the efficacy of SHP647 in inducing remission, based on composite score of patient-reported symptoms and centrally read endoscopy, in subjects with moderate to severe ulcerative colitis (UC).

Phase

The primary objectives of this study are to evaluate the safety and efficacy of filgotinib in the induction and maintenance treatment of moderately to severely active ulcerative colitis (UC) in participants who are biologic-naive and biologic-experienced. Participants who complete the study, or do not meet protocol response or remission criteria ...

Phase

The primary objective of this study is to evaluate the testicular safety of filgotinib in adult males with moderately to severely active ulcerative colitis.

Phase

This Phase 2 study is designed to evaluate the efficacy and safety of itacitinib in men and women with moderate to severe UC. The study consists of Part A and Part B, which consist of 12 weeks of double-blind, randomized, placebo-controlled treatment periods followed by 40 weeks open label extension ...

Phase

Ulcerative Colitis (UC) is another form of inflammatory bowel disease (IBS). Unlike Crohn’s, which can affect any part of the digestive tract, UC only affects the colon and rectum. This disease causes ulcers in the lining of the large intestine, but can affect the entire colon. What Causes Ulcerative Colitis? ...

Phase N/A

Phase 2 Dose-finding IMU-838 for Ulcerative Colitis

The investigational medicinal product (IMP) IMU-838 (vidofludimus calcium) is a new compound that selectively inhibits the human enzyme dihydroorotate dehydrogenase (DHODH). Dihydroorotate dehydrogenase plays a major role in the de-novo pyrimidine synthesis and is specifically expressed at high levels in proliferating or activated lymphocytes. Resting lymphocytes satisfy their pyrimidine requirements ...

Phase