Arthritis and Arthritic Pain Clinical Trials

A listing of Arthritis and Arthritic Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 218 clinical trials
Strategies Towards Personalised Treatment in Juvenile Idiopathic Arthritis (JIA).

Inhibitors of tumour necrosis factor (TNFa) reduce inflammation in patients with juvenile idiopathic arthritis (JIA), but only 20-40 percent achieve a state of no or very little disease activity. Tailored glucocorticoid joint injections are widely used (usually in general anaesthesia), but no controlled studies have addressed the effect of this …

  • 14 May, 2021
  • 5 locations
Efficacy of Secukinumab Compared to Ustekinumab in Adults With Active Psoriatic Arthritis and Failure of TNF -Inhibitor Treatment

The purpose of this study is to compare the safety and efficacy of secukinumab and ustekinumab in patients with active psoriatic arthritis who showed failure to previous TNF-inhibitor treatment

rheumatoid factor
plaque psoriasis
  • 21 Jul, 2021
  • 27 locations
Molecular Effects of Apremilast in the Synovium of Psoriatic Arthritis Patients

This study assess the genomics profiles in synovial biopsies obtained prior to, and 24 weeks after an immunomodulator agent (Apremilast) in patients with active psoriatic arthritis who are naive to treatment with a conventional synthetic DMARDs (such as methotrexate).

  • 27 Jan, 2021
  • 1 location
Diet Interventions in Psoriatic Arthritis

The purpose of this study is to learn whether changing diet impacts psoriatic arthritis (PsA).

  • 07 Apr, 2021
  • 2 locations
Tablet-based Cognitive Behavioral Intervention for Older Adults With Arthritis Fatigue

The purpose of this project is to pilot test a long-term effect of Tab-G (tablet-based cognitive behavioral group education intervention). The investigators will evaluate the effect of Tab-G, relative to Tab-I (tablet-based cognitive behavioral individual education intervention) and usual care group, on (a) daily steps, (b) fatigue level, (c) self-efficacy …

  • 01 Jul, 2021
  • 1 location
Cam Type FAI is a Cause of Hip Pain in the Young Adult and a Precursor to OA

An abnormally formed hip joint (cam deformity) is a major cause of osteoarthritis (OA). Individuals may not experience any symptoms until OA is severe due to extensive cartilage loss and changes in underlying bone. A series of studies showed that the cam deformity can lead to the development of OA …

  • 02 Jul, 2021
  • 1 location
A Study to Investigate Efficacy Tolerability and Safety of ABY-035 in Patients With Active Psoriatic Arthritis

This is a Phase II, prospective, multicenter, randomized, double-blind, placebo-controlled, dosefinding trial in parallel-groups with primary endpoint at Week 16 (visit V9) to investigate the efficacy, tolerability, safety, pharmacokinetics and immunogenicity of ABY-035 in adult patients with PsA.

  • 30 Jan, 2021
  • 1 location
GOLimumab and Methotrexate Versus Methotrexate in Very Early PsA (GOLMEPsA)

An investigator-initiated double-blind, parallel-group randomised controlled trial of GOLimumab and Methotrexate versus Methotrexate in very early PsA using clinical and whole body MRI outcomes.

  • 23 Jan, 2021
  • 1 location
The MEDIPSA Clinical Trial

The main purpose of this study is to validate the positive effect of "Omnibiotic Stress Repair" on patients with active psoriatic Arthritis.

  • 28 Mar, 2021
  • 1 location
Efficacy of PRGF Supplementation After TMJ Arthrocentesis in Patients With TMJ Osteoarthritis

Temporomandibular joint (TMJ) osteoarthritis (OA) affects articulating tissues secondary to inflammation resulting in intracapsular pain. This prospective, double-blind randomized clinical trial will evaluate the relative efficacy of TMJ arthrocentesis with a supplementation of platelet-rich growth factors (PRGF) compared to TMJ arthrocentesis with a steroid supplementation (a known effective therapy) for …

  • 28 Apr, 2021
  • 1 location