Arthritis and Arthritic Pain Clinical Trials

A listing of Arthritis and Arthritic Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 214 clinical trials
Broccoli In Osteoarthritis

To determine whether dietary sulforaphane (SFN), naturally available from eating broccoli, improves pain in people with knee osteoarthritis (OA), the trial will compare broccoli soup (rich in SFN) with a soup, which does not contain broccoli (control), but looks and tastes the same. Sixty-four participants with moderate osteoarthritis, chosen at …

  • 0 views
  • 15 May, 2021
  • 2 locations
Characterizing Rheumatoid Arthritis With 68Ga-FAPI PET/CT

68Ga-FAPI has been developed as a tumor-targeting agent as fibroblast activation protein is overexpressed in cancer-associated fibroblasts and some inflammation, such as IgG4-related disease and inflammatory bowel disease. Some researches identified FAP expression in synovial samples taken from both rheumatoid arthritis and osteoarthritis patients.Thus this prospective study is going to …

  • 0 views
  • 28 Jan, 2021
  • 1 location
Low-dose Colchicine With or Without Stepwise Dose Titration of Febuxostat for Flare Prophylaxis in Gout

The purpose of this study is to compare the incidence rate of gout flare for subjects with gout and hyperuricemia treated by two different starting doses of febuxostat.

  • 0 views
  • 28 Jan, 2021
  • 1 location
Safety Tolerability and Preliminary Efficacy of Multiple Intra-articular Injections of LRX712 in Patients With Knee OA

This study will explore the preliminary efficacy of multiple intra-articular injections of LRX712 by evaluating the ability of the drug to restore structural integrity of articular cartilage. Efficacy will be evaluated in the context of the systemic safety and local tolerability of the investigational drug.

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  • 74 views
  • 16 May, 2021
  • 1 location
The Combined Use of PRP With Lipoaspirate and/or Bone Marrow Aspirate in Osteoarthritis

To demonstrate the efficacy of the combined use of platelet-rich plasma (PRP) with lipoaspirate and/or bone marrow aspirate in osteoarthritis of major joints, and to compare the outcomes achieved using three combinations: PRP plus lipoaspirate, PRP plus bone marrow aspirate, and PRP plus both lipoaspirate and bone marrow aspirate.

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  • 42 views
  • 18 Mar, 2021
  • 1 location
Geniculate Artery Embolization for Treatment of Osteoarthritis

Single-arm, single-center, no sham or placebo, prospective pilot trial designed to evaluate the feasibility and safety of transcatheter arterial embolization in patients with mild to moderate radiographic knee OA. Eligible participants will receive geniculate artery embolization using Embozene Color-Advanced Microspheres. Patients will be followed up for a total of 12 …

  • 0 views
  • 18 Feb, 2021
  • 1 location
Functionally Aligned vs Mechanical Axis Aligned Total Knee Arthroplasty

The objective of this study is to compare clinical and radiological outcomes in robotic-arm assisted TKA using mechanical alignment (MA TKA) versus robotic-arm assisted TKA with functional alignment (FA TKA). Both FA TKA and MA TKA are performed through similar skin incisions, robotic-guidance, and use identical implants. In MA TKA, …

  • 0 views
  • 17 Feb, 2021
  • 2 locations
Clinical Trial of Electroacupuncture in Axial Spondyloarthritis (E-AcuSpA)

Axial spondyloarthritis (AxSpA) is a chronic disease that causes severe disability and poor quality of life. Current treatment options are limited and there are still significant non-responders to current western medications. Manual acupuncture has been shown to reduce pain in patients with AxSpA. There have been reports of electroacupuncture demonstrating …

  • 0 views
  • 09 Mar, 2021
  • 1 location
Trichomylin Safety Tolerability and Pharmacokinetics in Healthy Adults and First in Human Osteoarthritis Pain Evaluation

This is a first in human, randomized, double blind, SAD (with food effect) followed by a MAD study of Trichomylin conducted in healthy adult participants.

  • 0 views
  • 19 Jun, 2021
  • 1 location
Evaluation of the Use of Tranexamic Acid in Tibial Osteotomies

A randomised controlled double-blind clinical trial focused on the evaluation of the effectiveness of the tranexamic acid on bleeding, pain and wound complications reduction in tibial osteotomies. All the 84 included patients will be randomized in one of the two arms, will undergo to a tibial osteotomy and then will …

  • 0 views
  • 19 Mar, 2021
  • 1 location