Arthritis and Arthritic Pain Clinical Trials

A listing of Arthritis and Arthritic Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 214 clinical trials
Spinals in THA (Total Hip Arthroplasty)

Spinal anesthesia is commonly used in patients undergoing total hip replacements. The purpose of this study is to compare lidocaine to bupivacaine spinal anesthesia in patients having a total hip arthroplasty (THA). The objective of this study is to compare the two spinal anesthesia treatments in regards to transient neurological …

hip replacement
joint reconstruction
hip arthroplasty
  • 10 Mar, 2021
  • 2 locations
Improvement of Implant Survival in Total Joint Arthroplasty of the Trapeziometacarpal Joint

The study evaluates implant survival in total joint arthroplasty of the Trapeziometacarpal (TMC) joint by monitoring the survival of different implant types using radiostereometry (RSA) evaluation of the implants.

joint reconstruction
radiostereometric analysis
  • 23 Jan, 2021
  • 1 location
Pinnacle RSA Study

The primary objective is to establish the mean superior cup migration of the Pinnacle Acetabular Shell using model-based RSA over the first two years post-implantation. The primary endpoint is the mean vertical subsidence (Y translation, also known as superior cup migration) at 2 years as measured with RSA. This will …

traumatic arthritis
rheumatoid arthritis
congenital hip dysplasia
  • 26 Apr, 2021
  • 3 locations
Abatacept in Individuals Who aRe Considered At Risk of Developing Inflammatory Arthritis

Phase II, single-centre, open label, two parallel arm cohort randomised controlled trial (RCT) testing abatacept in a population of anti-CCP Ab positive individuals at moderate to high risk of developing IA according to a published risk score, already followed in the observational study 'CCP: Next Generation'

  • 24 Jan, 2021
  • 1 location
Medacta GMK Sphere Multicenter Post-Market Outcomes Study

This study is to average Forgotten Knee Score (FJS) of those patients receiving the Medacta GMK Sphere knee at the two and five year time points. 70 subjects, enrolled at the data coordinating center in Medacta GMK Sphere vs Posterior Stabilized study (WIRB Pro Num: 20141994) and randomized to the …

traumatic arthritis
joint reconstruction
total knee replacement
avascular necrosis
  • 25 Jan, 2021
  • 4 locations
Comparison of Functional Outcome in Patients After Hip Arthroplasty Depending on Surgical Approach

The aim of the study will be to compare functional outcomes of the two surgical hip approaches in total hip arthroplasty: anterior, posterolateral and anterolateral. Surgical approach may have influence on patients functional outcome.

joint reconstruction
hip arthroplasty
  • 18 Jul, 2021
  • 2 locations
Chronic Pain Master Protocol (CPMP): A Study of LY3556050 in Participants With Osteoarthritis

This study is being done to test the safety and efficacy of LY3556050 for the treatment of osteoarthritis pain. This trial is part of the chronic pain master protocol (H0P-MC-CPMP) which is a protocol to accelerate the development of new treatments for chronic pain.

body mass index
chronic pain
knee pain
  • 23 Jul, 2021
  • 46 locations
Clinical Trial on the Articular Pain With a Cucumber Supplement in Patients Diagnosed With Arthrosis

Randomized, controlled, double-blind clinical trial of two parallel branches to analyze the efficacy of a supplement extracted from the cucumber on the joint pain of patients diagnosed with osteoarthritis.

pain assessment
steroidal anti-inflammatory drugs
knee pain
  • 09 May, 2021
  • 1 location
Physical Activity Pathway for Patients With Osteoarthritis in Primary Care (OA-PCP) (R33)

The purpose of this study is to test an osteoarthritis (OA) primary care Physical activity Care Pathway (OA-PCP), a scalable intervention that includes: 1) a practical process for physical inactivity screening in primary care, 2) a brief, tailored physical activity (PA) counseling intervention via telephone, 3) connection of patients with …

  • 27 Apr, 2021
  • 1 location
Capability of Tofacitinib or Etanercept to Accelerate Tapering of NSAID and Treat-to-target Guided De-escalation of Corticosteroids in RA Patients

Patients with active rheumatic arthritis (RA) and lack of efficacy of at least one csDMARD (Disease-modifying anti-rheumatic drug) treatment will be randomized to receive either Tofacitinib (TOFA) or etanercept (ETA). The study will be separated into two parts: The capability to decrease and discontinue pain-reducing treatment with a NSAID (non-steroidal …

rheumatic diseases
  • 25 Jan, 2021
  • 6 locations