Arthritis and Arthritic Pain Clinical Trials

A listing of Arthritis and Arthritic Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 214 clinical trials
PCORI Integrated Care (IC) Models for Patient-Centered Outcomes

Multiple chronic conditions (MCC) are widely recognized as the U.S. public health challenge of the 21st century. These physical and behavioral health conditions take a large toll on those suffering from the diseases, including many who are publicly insured, as well as caregivers and society. While evidence-based integrated care models …

depressed mood
drugs of abuse
pulmonary disease
  • 08 Jul, 2021
  • 1 location
Study of Efficacy Safety and Tolerability of LNA043 in Patients With Knee Osteoarthritis

The study will determine the optimal dosing regimen of LNA043 in patients with knee osteoarthritis (OA).

body mass index
  • 28 Jul, 2021
  • 10 locations
Deployment o the Multidisciplinary Prospective Cohort Imminent

Immune-mediated inflammatory diseases (IMIDs) most often affect young patients and have high impact on morbidity and mortality with a significant alteration in the quality of life of patients with professional, social and emotional repercussions. Beyond this burden, IMIDs share many common pathophysiological mechanisms and treatments, known as "targeted therapies". Despite …

disease or disorder
  • 24 May, 2021
  • 1 location
A Study of Ixekizumab (LY2439821) in Children With Juvenile Idiopathic Arthritis Categories of Enthesitis-related Arthritis (Including Juvenile Onset Ankylosing Spondylitis) and Juvenile Psoriatic Arthritis

The reason for this study is to see if the study drug ixekizumab is safe and effective in children with juvenile idiopathic arthritis (JIA) categories of enthesitis-related arthritis (ERA) (including juvenile onset ankylosing spondylitis [JoAS]) and juvenile psoriatic arthritis (JPsA).

  • 24 Jul, 2021
  • 47 locations
RCT Comparing Robotically-Assisted vs. Manually-Executed Total Knee Arthroplasties

This study will explore if there are any difference in functional outcomes between two different surgical procedures for total knee replacement: robot-assisted versus manually-executed total knee arthroplasty.

joint reconstruction
total knee replacement
  • 07 May, 2021
  • 3 locations
Short 3-week Antibiotic Treatment Versus 6 Weeks in Adults With Septic Arthritis of Native Joint

In France, the incidence of native joint infections is about 10 per 100 000 person-years, most commonly caused by S.aureus followed by b-haemolytic streptococci. French and international antibiotic guidelines, based on expert advice and retrospective studies, recommend intravenous antibiotics for two weeks, then oral for 4 weeks without evident link …

  • 27 Jan, 2021
  • 38 locations
Trial of Colchicine Versus Prednisone for the Treatment of Acute CPPD Arthritis

Chondrocalcinosis, recently renamed the calcium pyrophosphate deposition (CPPD) disease, is a very frequent affection of the elderly and causes very painful arthritis. International recommendations for the treatment of patients suffering from CPPD are based upon rare studies, not randomized, with small samples, and thus very weak scientific evidence. The treatment …

  • 13 Feb, 2021
  • 7 locations
A Study Evaluating the Efficacy of a Single Injection Autologous Adipose Derived Mesenchymal Stromal Cells in Patients With Knee Osteoarthritis

ASCs will be administered via intra-articular use into the knee joint affected by OA where they are expected to exert their therapeutic effects. The objective of this clinical trial is to generate efficacy and tolerability profiles of single injections of 2 dosages of autologous ASCs versus standard of care (placebo), …

osteoarthritis of knee
steroidal anti-inflammatory drugs
  • 24 Jan, 2021
  • 1 location
Reducing Recurrent Knee Flexion Contracture by Correcting Leg Length Discrepancy After Total Knee Arthroplasty for OA

Moving one's joints through their full range of motion (ROM) is crucial for health and wellbeing. Those who are unable to do so have difficulty carrying out simple activities like walking or feeding themselves. Lost joint ROM is called a contracture. Osteoarthritis (OA) is the most common form of arthritis. …

total knee replacement
  • 01 Feb, 2021
  • 1 location
Spinals in THA (Total Hip Arthroplasty)

Spinal anesthesia is commonly used in patients undergoing total hip replacements. The purpose of this study is to compare lidocaine to bupivacaine spinal anesthesia in patients having a total hip arthroplasty (THA). The objective of this study is to compare the two spinal anesthesia treatments in regards to transient neurological …

joint reconstruction
hip replacement
hip arthroplasty
  • 10 Mar, 2021
  • 2 locations