Search Medical Condition
Please enter condition
Please choose location from dropdown
Clear Trial Filters

Traumatic Brain Injury Clinical Trials

A listing of Traumatic Brain Injury medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (278) clinical trials

Pediatric Concussion Assessment of Rest and Exertion

Persistent post-concussive symptoms (PPCS) pose long-term challenges and can impact negatively patients' health-related quality of life and functional outcomes. Preventing PPCS, pediatric concussion guidelines call for cognitive and physical rest. Strict physical activity restriction is recommended until symptom-free, followed by a progressive step-wise return to activities. Unfortunately, little evidence beyond ...

Phase N/A

Cortical Contributions to Motor Sequence Learning

Recent findings in humans suggest that motor sequences are represented in the premotor cortex once learned. Studies in animal models have also shown that the premotor cortical areas encode sequence-specific information. However, it is currently unknown if premotor cortical areas are involved in the acquisition or consolidation of sequences in ...

Phase N/A

Use of Adipose-Derived Stem/Stromal Cells in Concussion and Traumatic Brain Injuries

Concussion Syndrome (CS) and TBI are common injuries producing temporary and long-term damage to impact brain function. Symptoms are sometimes transient, sometimes long-term depending on severity and/or repetitive damage. Signs varying from recurrent headaches, mental fog, emotional changes to physical signs of loss of consciousness, amnesia to behavioral change (irritability, ...


Enhancing Brain Training With Virtual Reality

Brain training is a large and a growing field, both scientifically and commercially. Emerging evidence demonstrates that training can promote beneficial brain plasticity in both healthy individuals and clinical populations. Much of the recent interest in brain training can be traced back to the seminal work done at the University ...

Phase N/A

MAPLES Pilot Study for Low Mood in ABI

Low mood and depression are common following acquired brain injury (ABI). There is a lack evidence on effective treatments in ABI. Behavioural Activation (BA) is a potentially valuable option. People with low mood can have problems imagining, planning and engaging in positive activities, or avoid activities due to fear of ...

Phase N/A

Concussion Symptom Treatment and Education Program (C-STEP) in Post-Concussion Syndrome

This prospective randomized intervention study aims to determine if C-STEP improves outcomes for children with post-concussion syndrome. Forty children with post-concussion syndrome referred to the Nationwide Children's Hospital (NCH) Complex Concussion Clinic will be randomized to receive either usual care in the NCH Complex Concussion Clinic (comparison) or usual care ...

Phase N/A

Advancing Understanding of Transportation Options

The investigators will use a multi-site, two-armed randomized controlled trial of older drivers (n=300; 70 years) from clinical settings, and one family member each (n=up to 300), with longitudinal follow-up. Study goals are to test how much the DDA improves outcomes and identify who benefits most from the DDA. Evaluation ...

Phase N/A

Movement-2-Music: Lakeshore Examination of Activity Disability and Exercise Response Study

The proposed intervention efficacy trial will examine a rhythmic-based movement-2-music (M2M) intervention with 108 adults with physical/mobility disabilities who will be randomized into one of two groups: a) M2M or b) waitlist control. The primary aim is to determine the effects of a 12-week M2M intervention on physical and psychosocial ...

Phase N/A

Exploring the Effectiveness of Sensor-based Balance Training on Patient Outcome Measures

Individuals suffering from certain disorders/diseases including diabetes, arthritis, cancer, osteoarthritis, stroke, Parkinson's disease, cognitive impairment or brain Injury are more likely to experience a fall or a fall-related injury than healthy individuals during to impaired postural stability or diminished joint perception. Under certain circumstance they may also experience pain, depression, ...

Phase N/A

Validation and Standardization of a Battery Evaluation of the Socio-emotional Functions in Various Neurological Pathologies

The role of disorders of socio-emotional processes in cerebral diseases such as Alzheimer's disease, frontal temporal dementia, Parkinson's disease, Huntington's disease, traumatic brain injury, stroke, focal lesions, has been recognized recently. Social cognition refers to a large group of emotional and cognitive abilities regulating inter-individuals relationships and it includes mainly ...

Phase N/A