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Traumatic Brain Injury Clinical Trials

A listing of Traumatic Brain Injury medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (363) clinical trials

Assessing Brain Changes Throughout the WCBH Program

Symptoms resulting from mild/moderate trauma to the brain are as varied as the individuals who sustain them. The currently held belief is that the majority of healing and functional recovery occurs within the first two years post injury. A large proportion of individuals who sustain mild/moderate brain injuries (mTBIs) do ...

Phase N/A

Lactate Therapy After Traumatic Brain Injury

Study: Prospective, single-centre phase II interventional study. The study will take place at the Department of Intensive Care Medicine, Lausanne University Medical Center (Centre Hospitalier Universitaire Vaudois, CHUV), Lausanne, Switzerland. Patient population: Patients will be monitored with an intra-parenchymal monitoring system, consisting of ICP (Codman, Integra Neurosciences), PbtO2 (Licox, Integra ...

Phase N/A

Rehabilitation of Social Cognition in Subjects With Traumatic Brain Injury

The ability of the individual to know how to adopt the perspective of the other or be able to interpret and correctly identify their emotions, is essential for their proper development in society. The term Social Cognition would be the construct that would encompass these cognitive processes. People who have ...

Phase N/A

Brain Network Disruptions Related to Traumatic Coma

So far, the gold standard for neuroprognostication of severe traumatic brain injury (TBI) or anoxic encephalopathy is the bedside behavioural evaluation. Nevertheless, the predictive value of such an exclusive clinical approach has been consistently reported as limited and insufficient in this challenging clinical setting. Recent theoretical and experimental data converge ...

Phase N/A

Improving Ambulatory Community Access After Paralysis

In a surgical procedure electrodes are inserted into muscles of the lower extremities to correct hip, knee and ankle function. The electrode leads are connected to an implanted pulse generator located in the abdomen. After a typical post-operative period of two to five days, the recipient will be discharged home ...


The Effects of Acupuncture on the Risk of AD After TBI

Traumatic brain injury (TBI) is a severely disabling injury which affects 150-200 people per million annually. Increasing evidence suggests that TBI may be a major risk of dementia, Alzheimer's disease (AD) in particular. Postmortem evidence has shown that beta-amyloid (A) deposits, one of the most validated pathological biomarkers of AD, ...

Phase N/A

Thalamic Low Intensity Focused Ultrasound in Acute Brain Injury

Few neurological conditions are as scientifically mysterious and clinically, legally, and ethically challenging as disorders of consciousness (DOC). Typically developed after severe brain injury, this set of related conditions includes Coma, the Vegetative State (VS) and the Minimally Conscious State (MCS). In the past 20 years, an increasing amount of ...

Phase N/A

Cognitive Motion-Based Videogames Exploratory Study in Acquired Brain Injury

This study includes three experimental arms to research cognitive video games involving motion interaction in ABI population. The study consists of 4 primary phases: recruitment, assessment, intervention and post-intervention assessment. Two arms involve a randomized controlled study with inpatient participants, where participants are randomly assigned to an intervention or control ...

Phase N/A

Amplitude-integrated EEG in Improvement of Seizure Detection and Prognostication in Children With TBI

Children with moderate to severe TBI are at risk of significant long-term neurological sequelae. Careful post-injury management is crucial in optimizing their recovery. Seizures are a frequent complication. They are associated with worse outcome and require prompt intervention. However, they are often subclinical and are only detectable by gold-standard conventional ...

Phase N/A

Anosognosia Evaluation After Cranocerebral Trauma Moderate to Severe

This experimental protocol is proposed to 40 patients who have a moderate or severe traumatic brain injury. All of this protocol is 2 hours, tasks are administered in the order named. To measure anosognosia, this protocol is to administer 4 questionnaires used in clinical routine who have proposed to patients ...

Phase N/A