T-Cell Lymphoma Clinical Trials

A listing of T-Cell Lymphoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 186 clinical trials
Lenalidomide and Ipilimumab After Stem Cell Transplant in Treating Patients With Hematologic or Lymphoid Malignancies

This pilot clinical trial studies the side effects of lenalidomide and ipilimumab after stem cell transplant in treating patients with hematologic or lymphoid malignancies. Biological therapies, such as lenalidomide, may stimulate or suppress the immune system in different ways and stop cancer cells from growing. Immunotherapy with monoclonal antibodies, such …

lenalidomide
absolute neutrophil count
cancer chemotherapy
forced expiratory volume
ejection fraction
  • 37 views
  • 24 Jan, 2021
  • 2 locations
Evaluation of Human Immune Responses to Influenza Virus Vaccination in Patients With Lymphoma

This clinical trial evaluates the influenza virus vaccination in evaluating human immune response in patients with lymphoma. Evaluating immune response may increase the understanding of how the immune system changes when patients receive treatment for lymphomas by looking at the antibody levels and the level of the different cells that …

leukemia
ibrutinib
lymphocytic leukemia
peripheral t-cell lymphoma
diffuse large b-cell lymphoma
  • 33 views
  • 25 Jan, 2021
  • 1 location
Pembrolizumab in Treating Patients With Stage IB-IV Mycosis Fungoides

This phase II trial studies how well pembrolizumab works in treating patients with stage IB-IV mycosis fungoides. Antibodies, such as pembrolizumab, may interfere with the ability of cancer cells to grow and spread.

erythropoietin
metastatic tumor
serum pregnancy test
neutrophil count
pembrolizumab
  • 1 views
  • 06 Mar, 2021
  • 1 location
Study Evaluating GZ17-6.02 in Patients With Advanced Solid Tumors or Lymphoma

This study will evaluate the safety, pharmacokinetics, and pharmacodynamic effects of a novel anti-cancer drug, GZ17-6.02 administered to patients with advanced solid tumors or lymphoma, which have progressed after receiving standard/approved therapy or where there is no approved therapy.

cancer chemotherapy
kidney function tests
coagulants
cancer
platelet count
  • 24 views
  • 26 Jan, 2021
  • 3 locations
A Phase 1/2 Study of In Situ Vaccination With Tremelimumab and IV Durvalumab Plus PolyICLC in Subjects With Advanced Measurable Biopsy-accessible Cancers

This is an open-label, multicenter Phase 1/2 study of the CTLA-4 antibody, tremelimumab, and the PD-L1 antibody, durvalumab (MEDI4736), in combination with the tumor microenvironment (TME) modulator polyICLC, a TLR3 agonist, in subjects with advanced, measurable, biopsy-accessible cancers.

cytotoxic t-lymphocyte antigen 4
sarcoma
cancer
durvalumab
poly iclc
  • 0 views
  • 03 Mar, 2021
  • 7 locations
Study to Assess Safety Tolerability Pharmacokinetics and Antitumor Activity of AZD4573 in Relapsed/Refractory Haematological Malignancies

The purpose of this study is to assess the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD) and preliminary antitumor activity of AZD4573 in subjects with relapsed or refractory haematological malignancies.

hodgkin's disease
progressive disease
leukemia
secondary aml
azd4573
  • 98 views
  • 31 Mar, 2021
  • 17 locations
Talimogene Laherparepvec and Nivolumab in Treating Patients With Refractory Lymphomas or Advanced or Refractory Non-melanoma Skin Cancers

This phase II trial studies how well talimogene laherparepvec and nivolumab work in treating patients with lymphomas that do not responded to treatment (refractory) or non-melanoma skin cancers that have spread to other places in the body (advanced) or do not responded to treatment. Biological therapies, such as talimogene laherparepvec, …

adenocarcinoma
avelumab
peripheral t-cell lymphoma
mucin
gilbert's syndrome
  • 453 views
  • 14 Apr, 2021
  • 19 locations
A Phase 1 Dose-Escalation and Cohort-Expansion of VLS-101 in Hematologic Malignancies

This is a Phase 1 study evaluating the safety, pharmacokinetics, pharmacodynamics, immunogenicity, and efficacy of VLS-101, an antibody-drug conjugate (ADC) that targets receptor tyrosine kinase-like orphan receptor 1 (ROR1) on cancer cells. The study is evaluating VLS-101 in patients with previously treated hematological cancers.

HIV Infection
cancer
bone marrow procedure
tyrosine
hematologic malignancy
  • 29 views
  • 08 Apr, 2021
  • 14 locations
Donor Stem Cell Transplant With Treosulfan Fludarabine and Total-Body Irradiation for the Treatment of Hematological Malignancies

This phase II trial studies how well a donor stem cell transplant, treosulfan, fludarabine, and total-body irradiation work in treating patients with blood cancers (hematological malignancies). Giving chemotherapy and total-body irradiation before a donor stem cell transplant helps stop the growth of cells in the bone marrow, including normal blood-forming …

  • 0 views
  • 29 Mar, 2021
  • 1 location
Fludarabine Phosphate Cyclophosphamide Total Body Irradiation and Donor Stem Cell Transplant in Treating Patients With Blood Cancer

This phase II trial studies how well fludarabine phosphate, cyclophosphamide, total body irradiation, and donor stem cell transplant work in treating patients with blood cancer. Drugs used in chemotherapy, such as fludarabine phosphate and cyclophosphamide, work in different ways to stop the growth of cancer cells, either by killing the …

fludarabine
secondary aml
lymphoproliferative disease
blood stem cell transplant
secondary myelodysplastic syndrome
  • 134 views
  • 24 Jan, 2021
  • 1 location