Systemic Lupus Erythematosus Clinical Trials

A listing of Systemic Lupus Erythematosus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 230 clinical trials
A Study of LY3471851 in Adults With Systemic Lupus Erythematosus (SLE)

The reason for this study is to see if the study drug LY3471851 (NKTR-358) is safe and effective in adults with systemic lupus erythematosus (SLE).

lupus
antinuclear antibody
rash
arthritis
  • 79 views
  • 12 Sep, 2021
  • 151 locations
Hydroxychloroquine (HCQ) for Recurrent Pregnancy Loss

treatment to improve the chance of a live birth. Exciting indications for using Hydroxychloroquine (HCQ) include: Malaria profylaxis and treatment, systemic and discoid lupus erythematosus (SLE) and

discoid lupus erythematosus
malaria
  • 6 views
  • 24 Jan, 2021
  • 1 location
Hydroxychloroquine in Prevention of Preeclampsia

such as systemic lupus erythematosus, antiphospholipid syndrome and placental inflammatory lesions such as chronic histiocytic intervillositis, hydroxychloroquine has therapeutic potential to improve

  • 0 views
  • 29 Jul, 2021
  • 1 location
Subcutaneous Anifrolumab in Adult Patients With Systemic Lupus Erythematosus

The purpose of this study is evaluating the efficacy and safety of SC antifrolumab in adult patients with moderate -to-severe SLE despite receiving standard therapy

lupus
anifrolumab
  • 0 views
  • 12 Sep, 2021
  • 92 locations
A Clinical Study to Evaluate the Potential Role of ACTH Gel in Patients With Scleritis

or on a regular basis (maintenance) in people with systemic lupus erythematosus (lupus), infantile spasms, adults with acute relapses or flares of multiple sclerosis (MS), patients with kidney

  • 1 views
  • 16 Aug, 2021
  • 5 locations
A DOSE-RANGING STUDY TO EVALUATE EFFICACY AND SAFETY OF PF-06700841 IN SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)

Assessment of PF-06700841 in participants with moderate to severe active, generalized Systemic Lupus Erythematosus (SLE) that have inadequate response to standard of care.

leflunomide
lupus
mycophenolate
methotrexate
azathioprine
  • 198 views
  • 15 Sep, 2021
  • 227 locations
A Study of KZR-616 in Patients With SLE With and Without Lupus Nephritis

This is a Phase 1b/2, multi-center study in which patients will receive KZR-616, administered as a subcutaneous (SC) injection weekly for 13 weeks (Phase 1b) or 24 weeks (Phase 2).

glucocorticoids
kidney biopsy
antimalarial agents
leflunomide
mammogram
  • 261 views
  • 08 Sep, 2021
  • 53 locations
A Study Evaluating the Effects of GLPG3970 Given as Oral Treatment for 12 Weeks in Adults With Systemic Lupus Erythematosus

This is a first exploration of GLPG3970 in subjects with active systemic lupus erythematosus (SLE) to evaluate the effect on disease biomarkers and to determine its pharmacokinetics (PK) profile

quinacrine
azathioprine
nsaids
corticosteroids
prednisone
  • 0 views
  • 22 Aug, 2021
  • 14 locations
MEK and Autophagy Inhibition in Metastatic/Locally Advanced Unresectable Neuroblastoma RAS (NRAS) Melanoma

dosing of 2 milligrams (mg) once a day. Hydroxychloroquine (PLAQUENILR) is an orally available autophagy inhibitor that has been used for many years to treat autoimmune diseases like lupus, sarcoidosis

  • 0 views
  • 25 Jan, 2021
  • 5 locations
A Study of Guselkumab in Participants With Active Lupus Nephritis

The purpose of this study is to evaluate the efficacy of guselkumab in participants with active lupus nephritis (LN).

glucocorticoids
angiotensin
mycophenolic acid
kidney biopsy
mammogram
  • 1 views
  • 08 Sep, 2021
  • 72 locations