Systemic Lupus Erythematosus Clinical Trials

A listing of Systemic Lupus Erythematosus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 230 clinical trials
The Clinical Features and Pregnancy Outcomes of CTD Patients

Connective tissue disease (CTD) is a common group of autoimmune diseases, mainly including systemic lupus erythematosus (SLE), antiphospholipid syndrome (APS) , and so on. APS is caused by

  • 0 views
  • 21 Aug, 2021
  • 1 location
Development of a Therapeutic Endpoint in Pediatric Rheumatologic Conditions

The overarching goal of this study is the development of a physiologic endpoint of pain and treatment effect in three distinct rheumatology populations. This would enable objective assessment of pain and treatment in these populations and enable a much more precise approach to treatment. Such an endpoint stands to significantly …

  • 0 views
  • 15 Aug, 2021
  • 1 location
Volatile Organic Compounds (VOCs) as a Biomarker in Immune-mediated Pulmonary Arterial Hypertension (PAH)

hypothesize that at time of diagnosis the VOC profiles will discriminate patients with PAH-CTD and idiopathic PAH (IPAH) from patients with systemic sclerosis or systemic lupus erythematosus (CTD) without PAH

lupus
hypertension
connective tissue disease
progressive systemic sclerosis
heart disease
  • 1 views
  • 15 Sep, 2021
  • 1 location
Meir Medical Center Rheumatologic Biobank

Serum, synovial fluid and skin biopsies from patients will be collected to the biobank with rheumatoid diseases. These samples will later be used for clinical and basic research, following approval of each specific study by the IRB. The investigators intend to extract protein, DNA and RNA from each sample.

  • 0 views
  • 22 Jan, 2021
  • 1 location
Exploring Immune Cell Signatures in Autoimmunity and Dry Eye Syndrome

nerve/dendritic cell morphology interact in 3 rheumatological conditions: Sjogren's syndrome (SS), Rheumatoid arthritis (RA), Systemic lupus erythematosus (SLE). The preliminary flow cytometric

meibomian gland dysfunction
erythema
confocal microscopy
burning sensation
ocular surface disease
  • 86 views
  • 25 Jan, 2021
  • 1 location
Role of T Follicular Helper Cells in Autoimmune Hemolytic Anemia (TFH in AIHA)

T follicular helper (TFH) cells represent a T cell subset dedicated to the activation of B cells. They have been involved in the pathogenesis of autoimmune diseases in humans such as lupus and

lupus
  • 9 views
  • 01 Jul, 2021
  • 1 location
Hydroxychloroquine Blood Levels in Primary Sj gren Syndrome Patients

. However, there are no studies that evaluated whether blood levels of HCQ could influence in the therapeutic response, as has been reported in systemic lupus erythematosus (SLE). Objectives

  • 0 views
  • 26 Jan, 2021
  • 2 locations
Role of Fcgamma Receptors in Immune Thrombocytopenia (ITP)

and systemic lupus erythematous. The aim of this study is to compare the expression of FcR in patients with ITP on circulating monocytes and on splenic macrophages.

lupus
autoimmune disease
thrombocytopenia
arthritis
autoimmune thrombocytopenia
  • 12 views
  • 01 Jul, 2021
  • 1 location
Genotype-Phenotype Study of Patients With Plaquenil -Induced Retinal Toxicity With Evaluation of the ABCA4 Gene

Background Plaquenil (hydroxychloroquine) is an anti-inflammatory drug that is used to treat some autoimmune diseases such as lupus and rheumatoid arthritis. This

blindness
eye exam
hydroxychloroquine
  • 4 views
  • 12 Sep, 2021
  • 1 location
The Effect of Methotrexate on Sperm Quality in Men With Inflammatory Bowel Disease

gastrointestinal tract. MTX has been studied for many years and in used as treatment in not only IBD, but also in conditions such as rheumatoid arthritis and lupus. However, due to concerns about the safety of MTX

enteropathy
folic acid
tumor necrosis factor
ulceration
chronic disease
  • 43 views
  • 21 Jul, 2021
  • 1 location