Systemic Lupus Erythematosus Clinical Trials

A listing of Systemic Lupus Erythematosus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 22 clinical trials
Hydroxychloroquine in Individuals At-risk for Type 1 Diabetes Mellitus

The study is a 2-arm, double blinded, multicenter, 2:1 randomized, placebo controlled clinical trial. Subjects will receive hydroxychloroquine or placebo and close monitoring for progression of T1D.

  • 190 views
  • 01 Aug, 2021
  • 46 locations
A Study of LY3471851 in Adults With Systemic Lupus Erythematosus (SLE)

The reason for this study is to see if the study drug LY3471851 (NKTR-358) is safe and effective in adults with systemic lupus erythematosus (SLE).

lupus
rash
arthritis
antinuclear antibody
  • 79 views
  • 31 Jul, 2021
  • 147 locations
A Study of Baricitinib in Participants With Systemic Lupus Erythematosus (SLE)

The reason for this long term study is to see how safe and effective the study drug known as baricitinib is in participants with systemic lupus erythematosus (SLE) who have completed the final

lupus
  • 503 views
  • 31 Jul, 2021
  • 557 locations
Subcutaneous Anifrolumab in Adult Patients With Systemic Lupus Erythematosus

The purpose of this study is evaluating the efficacy and safety of SC antifrolumab in adult patients with moderate -to-severe SLE despite receiving standard therapy

lupus
anifrolumab
  • 0 views
  • 01 Aug, 2021
  • 87 locations
A DOSE-RANGING STUDY TO EVALUATE EFFICACY AND SAFETY OF PF-06700841 IN SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)

Assessment of PF-06700841 in participants with moderate to severe active, generalized Systemic Lupus Erythematosus (SLE) that have inadequate response to standard of care.

corticosteroids
azathioprine
lupus
methotrexate
antimalarials
  • 198 views
  • 01 Aug, 2021
  • 223 locations
A Study to Investigate the Safety and Efficacy of Elsubrutinib and Upadacitinib Given Alone or in Combination in Participants With Moderately to Severely Active Systemic Lupus Erythematosus (SLE)

The main objective of this study is to evaluate the safety and efficacy of elsubrutinib, upadacitinib, and ABBV-599 vs placebo for the treatment of signs and symptoms of Systemic Lupus

arthritis
lupus
methotrexate
antimalarials
mycophenolate
  • 413 views
  • 29 Jul, 2021
  • 313 locations
A Study of Guselkumab in Participants With Active Lupus Nephritis

The purpose of this study is to evaluate the efficacy of guselkumab in participants with active lupus nephritis (LN).

mammogram
nephritis
glucocorticoids
mycophenolate
kidney biopsy
  • 0 views
  • 01 Aug, 2021
  • 69 locations
Study of M5049 in CLE and SLE Participants

This study is to evaluate the safety, tolerability and pharmacokinetics (PK) of orally administered M5049 in participants with systemic lupus erythematosus (SLE) or cutaneous lupus erythematosus

lupus
cutaneous lupus
  • 0 views
  • 01 Aug, 2021
  • 10 locations
Safety Pharmacokinetics and Preliminary Efficacy Study of CFZ533 in Patients With Lupus Nephritis.

with moderately active lupus nephritis.

immunosuppressive agents
body mass index
systemic lupus erythematosus
nephritis
mycophenolate
  • 124 views
  • 31 Jul, 2021
  • 26 locations
Study of Safety Efficacy and Tolerability of Secukinumab Versus Placebo in Combination With SoC Therapy in Patients With Active Lupus Nephritis

active lupus nephritis (ISN/RPS Class III or IV, with or without co-existing class V features).

nephritis
mammogram
urinary sediment
glomerular filtration rate
  • 37 views
  • 30 Jul, 2021
  • 123 locations