Systemic Fungal Infections Clinical Trials

A listing of Systemic Fungal Infections medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 15 clinical trials
Evaluate F901318 Treatment of Invasive Fungal Infections in Patients Lacking Treatment Options (FORMULA-OLS)

A study to evaluate F901318 (study drug) for the treatment of invasive fungal infections in patients lacking suitable alternative treatment options.

fungal infection
  • 308 views
  • 04 Oct, 2022
  • 45 locations
A Phase 2, Open-Label, Single-Arm, Sequential-Panel Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Posaconazole (POS, MK-5592) Intravenous and Powder for Oral Suspension Formulations in Pediatric Participants From Birth to Less Than 2 Years of Age With Possible, Probable, or Proven Invasive Fungal Infection

This study aims to estimate the pharmacokinetics (PK) of posaconazole (POS, MK-5592) intravenous (IV) and powder for oral suspension (PFS) formulations in pediatric participants <2 years of age with invasive fungal infection (IFI).

  • 16 views
  • 28 Oct, 2022
  • 14 locations
A New Posaconazole Dosing Regimen for Paediatric Patients With Cystic Fibrosis and Aspergillus Infection

This study will provide: (1) new insights in the prevalence of Aspergillus infection in children and adolescents with CF aged 8-17 yrs; (2) an in silico modelled dose of posaconazole for children and adolescents with CF and Aspergillus infection aged 8-17 yrs; (3) an intensive sampling PK study to define …

itraconazole
voriconazole
fibrosis
respiratory symptom
posaconazole
  • 10 views
  • 26 Jul, 2021
  • 31 locations
Anti-fungal Strategies in Acute-on-Chronic Liver Failure Patients

Early treatment of invasive fungal infections (IFI) may prevent undue mortality in acute on chronic liver failure (ACLF) patients. We aim to study the impact of early empiric treatment (based on clinical suspicion) of IFI as compared to pre-emptive treatment (based on biomarkers and culture positivity) on the outcomes in …

pleuritic pain
invasive fungal infection
anti-fungal
encephalopathy
COPD
  • 2 views
  • 07 May, 2022
  • 1 location
RCT of IV Dexamethasone to Prevent Relapse in the Treatment of Migraine in a Paediatric ED

Background: Headaches is one of the most common complaints of children in the ED and the treatment of pediatric migraine is largely based on extrapolation data from adult studies, limited pediatric trials, clinical experience and expert consensus. Despite the fact that dexamethasone has already been proven effective to reduce recurrence …

acute migraine
prochlorperazine
Accepts healthy volunteers
naproxen
metoclopramide
  • 18 views
  • 11 May, 2022
  • 1 location
Studies of Human Pneumocystis Infection

This study will examine the effectiveness of a new laboratory method for detecting pneumocystis organisms in a salt-water (saline) oral wash. Pneumocystis infection in people with weakened immunity especially patients with HIV infection or cancer, organ transplant recipients and people receiving immune suppressing therapy can cause life-threatening pneumonia. Currently, pneumocystis …

pneumonia
pneumocystis carinii infection
Accepts healthy volunteers
cough
HIV Infection
  • 7 views
  • 24 Oct, 2022
  • 1 location
An Observational Study to Assess the Prevalence and Outcomes of Primary Pulmonary Coccidioidomycosis in Persons Aged > / = 14 Years Presenting With Community Acquired Pneumonia (CAP) in Endemic Areas (SAnds-PPC)

This is an observational study in 1,000 individuals aged 14 years or older, diagnosed with Community Acquired Pneumonia (CAP) who meet all eligibility criteria in Coccidioides endemic regions. This study is designed to provide data on the prevalence of primary pulmonary coccidioidomycosis among persons presenting with CAP in endemic regions. …

myalgia
pneumonia
chest radiograph
chest pain
cough
  • 170 views
  • 04 Oct, 2022
  • 6 locations
Prospective Data Bank Creation to Study Vaginal Conditions

The purpose of this study is to identify and elucidate the pattern and perhaps role of atypical proteins, cytokines and vaginal microbial flora in the pathogenic mechanisms involved in the development of vulvodynia, recurrent fungal and bacterial vaginosis and preterm labor.

bacterial vaginosis
Accepts healthy volunteers
preterm labor
cytokines
  • 284 views
  • 22 Oct, 2021
  • 1 location
Studies of Disorders With Increased Susceptibility to Fungal Infections

Background Researchers are interested in studying disorders that make individuals more susceptible to fungal infections, specifically infections with the Candida yeast. These disorders are often related to problems with the immune system and may have genetic factors, which suggests that researchers should study not only the individual with the disorder, …

myeloperoxidase deficiency
Accepts healthy volunteers
x-rays
ipex
immunoglobulin
  • 221 views
  • 23 Oct, 2022
  • 1 location
Vicente Ferrer HIV Cohort Study

The VFHCS is a long-term prospective cohort study of HIV infected patients from a resource-poor rural setting in India. The aim of the study is to use data collected from routine clinical care in order to describe the epidemiology of HIV and its related conditions in the investigators area, and …

HIV Vaccine
  • 76 views
  • 21 Mar, 2021
  • 1 location