Sjogren's Syndrome Clinical Trials

A listing of Sjogren's Syndrome medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 19 clinical trials
Nivolumab in Treating Patients With Autoimmune Disorders and Advanced Metastatic or Unresectable Cancer

This phase Ib trial studies the side effects of nivolumab and to see how well it works in treating patients with autoimmune disorders and cancer that has spread to other places in the body or cannot removed by surgery. Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's …

bladder cancer
human chorionic gonadotropin
head and neck cancer
  • 15 Sep, 2021
  • 29 locations
3-year Open-Label Study Evaluating Safety Tolerability and Efficacy of Lorecivivint in Subjects With Osteoarthritis of the Knee

This study is designed as a 3-year, multicenter, open-label study evaluating the safety, tolerability, and efficacy of intra-articular (IA) Lorecivivint (LOR) in subjects with osteoarthritis of the knee in a real-world setting.

  • 17 Sep, 2021
  • 4 locations
The PediQUEST Response Intervention Study

PediQUEST Response proposes a new system of care that expects to improve quality of life in children, adolescents, and young adults with advanced cancer and their parents. The investigators want to learn whether patients that are cared for using PediQUEST Response do in fact feel better than those receiving usual …

brain tumor
  • 16 Sep, 2021
  • 4 locations
Nebulized Lidocaine and Intranasal Midazolam for NGT Insertion in Children

Nasogastric tube (NGT) is a commonly performed procedure in the Emergency Department. Although it is not a major procedure, it is usually associated with a bad experience and cause discomfort and pain in kids. This randomized controlled double-blinded double-dummy trial aims to investigate the efficacy of local topical anesthetic and/or …

  • 03 Sep, 2021
  • 2 locations
Characterization of Diseases With Salivary Gland Involvement

Background Salivary glands in and around the mouth and throat make saliva. Salivary gland disorders can affect a person s quality of life. Studying people who have a disease that affects their salivary gland(s) may teach researchers about the disorders and their genetics. Objectives To study salivary gland diseases and …

cancer treatment
dry eyes
  • 15 Sep, 2021
  • 1 location
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases. This program allows patients and researchers to connect as easily as possible to help advance treatments and cures …

rare diseases
other disease
  • 08 Sep, 2021
  • 2 locations
The Pathogenesis and Natural History of Sjogren s Syndrome

Background -Sjogren s syndrome is a disease that affects about 1-4 million Americans. It is more common in women. It mainly affects the glands that produce saliva and tears, leading to dry eyes and dry mouth. The cause of Sjogren s syndrome is unknown, but inflammation plays an important role. …

keratoconjunctivitis sicca
dry eyes
  • 15 Sep, 2021
  • 1 location
Medico-economic and Quality of Life Impact of Sjogren-associated Small Fiber Neuropathy

%) between 40 and 60 years of age and main manifestations are generalized sicca syndrome (ocular, oral, cutaneous) and arthralgia. In 20% of cases, Sjgren's syndrome is associated with peripheral

skin biopsy
  • 05 Sep, 2021
  • 2 locations
Assessment of TFT by OCT in Healthy Subjects and Subjects With DES

Dry eye syndrome (DES) is a highly prevalent ocular condition with potential severe consequences for affected patients. DES can be either caused by decreased tear production or increased tear evaporation, both leading to an instable tear film. Despite many efforts, generally accepted methodologies to diagnose, assess the severity and monitor …

optical coherence tomography
burning sensation
schirmer's test
artificial tears
  • 15 Sep, 2021
  • 1 location