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Seizure Disorders Clinical Trials

A listing of Seizure Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (56) clinical trials

Rolandic Epilepsy/ESES/Landau-Kleffner Syndrome and Correlation With Language Impairment

This study investigates the relation between childhood epilepsy and language impairment. Functional MRI (fMRI) will be used to compare language and motor task related brain activation of children with epilepsy with healthy controls. Diffusion weighted MRI (DWI) will be used to assess differences in anatomical brain connectivity.

Phase N/A

Correlation Between SV2A Expression in Tumour Tissue and Efficacy of Levetiracetam in Glioma Patients With Epilepsy

Levetiracetam is a relatively novel anti-epileptic drug (AED), which has proven to be effective and well tolerated in many glioma patients with otherwise pharmacoresistant epilepsy. Moreover, levetiracetam has neither enzyme-inducing nor enzyme-inhibiting properties, which makes the drug particularly attractive for brain tumour patients, as they frequently receive chemotherapy and/or corticosteroids. ...

Phase

Role of Antibodies Against Glutamate Receptors and Double Stranded DNA in Epilepsy Patients

The investigators will check the serum of epilepsy patients for antibodies against glutamate receptors and double stranded DNA. They will characterise the patients (by the kind of epilepsy, autoimmune disease comorbidity, and cognitive profile).

Phase N/A

Mapping of the Epileptic Brain

This study aims improving the outcome after brain resective surgery of epileptic patients by improving presurgical evaluations. In particular the specific goal is to evaluate the ability of non invasive neuroimaging (functional magnetic resonance imaging and electroencephalography) to provide presurgical maps of the functional areas of the brain and of ...

Phase N/A

Longitudinal Early Epilepsy Study

The aim is to study the cognitive and brain development of children with absence epilepsy. In addition, this study aims to identify prognostic factors for cognitive deterioration and/or poor seizure control. Objective To study the development of cognition in children with absence epilepsy and the functional brain organization over time. ...

Phase N/A

Study of Specimens Obtained During Epilepsy Surgery

This is a protocol to perform research studies on tissues that are removed in the operating room during surgical procedures for drug resistant epilepsy. Our aim is to acquire and supply useful tissue specimens for intramural NIH research projects. The investigators will evaluate participants with medically intractable drug resistant epilepsy ...

Phase N/A

Human Epilepsy Project 2: Resistant Focal Seizures Study

The Epilepsy Foundation is launching a partnership, called the Human Epilepsy Project, in collaboration with the Epilepsy Study Consortium. This study (which is called HEP2 for short) is designed to better understand the challenges of living with focal seizures that do not respond to medication. The HEP2 study will follow ...

Phase N/A

A Natural History Study of hnRNP-related Disorders

Neurodevelopmental disorders are a group of disorders in which the development of the central nervous system is disturbed. The genetic basis for many neurodevelopmental disorders has continued to expand and a recent gene called HNRNPH2 (Heterogeneous Nuclear Ribonucleoprotein H2, encoded by HNRNPH2) is one such gene that is associated with ...

Phase N/A

Development of an Epileptic Seizure Detection Algorithm by Continuous Analysis of the Electrocardiogram

In a first step, the team will build a multi-parametric algorithm on existing records issued from the Epilepsy Monitoring Units. Each selected record will be analyzed by EMU medical team in order to detect seizure on the EEG. The algorithm will adapt in order to obtain the best sensitivity and ...

Phase N/A

Investigating Epilepsy: Screening Evaluation and Treatment

Objectives The primary objective is to screen patients who are referred to the NIH with a known or suspected diagnosis of epilepsy for eligibility to participate in ongoing epilepsy-related protocols. The secondary objectives are to provide standard of care evaluation and treatment of patients with drug-resistant epilepsy, to provide training ...

Phase N/A