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Seizure Disorders Clinical Trials

A listing of Seizure Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (213) clinical trials

Microburst Vagus Nerve Stimulator (VNS) Therapy Feasibility Study

Evaluate the initial safety and effectiveness of Microburst VNS stimulation in subjects with refractory epilepsy.

Phase

A Deep Brain Stimulation System in Epilepsy: Tracking Neural Excitability

The main purpose of this research project is to evaluate the safety and effectiveness of a surgically implanted device called the Medtronic Activa PC+S System in patients with medically refractory epilepsy (people who have seizures that are not completely controlled by medical therapy). The system sends small electrical pulses into ...

Phase N/A

CYPHP Evelina London Evaluation

The UK lags behind other highincome countries in several measures of child health, including mortality (Wolfe et al, 2013). The UK position relative to comparable European countries is poor in many regards, including higher allcause mortality, especially for infants and adolescents, and a slower decline in noncommunicable disease mortality (Viner ...

Phase N/A

Application of Novel Diagnostic and Therapeutical Methods in Epilepsy and Neurodevelopmental Abnormalities in Children.

The clinical part of EPIMARKER is composed of 2 prospective studies (WP1 and WP2) of epilepsy progress in Tuberous Sclerosis Complex -TSC children, performed in 2 sites: Medical University of Warsaw -WUM and Children's Memoroal Health Institute - IPCZD, Poland. WP1 and WP2 are designed to conduct the studies, but ...

Phase N/A

Post-market Study of AMAP Receptor Antagonists for Epilepsy Patients in Hong Kong

Epilepsy is a chronic neurological disease which affects approximately 70,000 patients in Hong Kong and 50 billion people worldwide. Among these patients, one-third remained unresponsive to antiepileptic agents. Continual drug manipulation is an essential therapeutic option for these patients with refractory epilepsy. In particular, rational polytherapy has become the mainstay ...

Phase N/A

Seizure Treatment in Glioma

Currently, treatment of glioma patients with a specific anti-epileptic drug (AED) mainly depends on the physicians' preference, as there is no robust evidence from randomized controlled trials supporting the use of one specific anticonvulsant above the other in glioma patients. Levetiracetam and valproic acid are the most commonly used AEDs ...

Phase

Amplitude-integrated EEG in Improvement of Seizure Detection and Prognostication in Children With TBI

Children with moderate to severe TBI are at risk of significant long-term neurological sequelae. Careful post-injury management is crucial in optimizing their recovery. Seizures are a frequent complication. They are associated with worse outcome and require prompt intervention. However, they are often subclinical and are only detectable by gold-standard conventional ...

Phase N/A

ZEDEBAC: Zebinix Effects in Dependency of Baseline Conditions

This is a non interventional prospective study. Centers will enroll adult participants with partial onset seizures with or without secondary generalisation for whom the clinician has decided to initiate ESL as an adjunctive therapy prior to the decision to take part in this study. Participants to be enrolled into the ...

Phase N/A

The Modified Ketogenic Diet for the Treatment of Pharmacoresistant Epilepsy in Adults

Epilepsy is a common neurological condition. Unfortunately, just over 30% of patients with epilepsy (PWE) do not become seizure free with anti-epileptic drugs. Some patients may be suitable for epilepsy surgery. Alternative established treatments include vagal nerve stimulation and the ketogenic diet in children. The evidence base for the use ...

Phase N/A

Electroencephalogram (EEG) Triggered Functional Magnetic Resonance Imaging (fMRI) in Epilepsy Patients

A prospective exploratory study in patients with drug resistant epilepsy with a target comparison of long term outcome. NeuroScan software modules and a MagLink will be used to acquire EEG in combination with MRI/fMRI data. The MagLink system is used for obtaining integrated EEG and Event Related Potential (ERP) recordings ...

Phase N/A