Seizure Disorders Clinical Trials

A listing of Seizure Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 127 clinical trials
Comparison of Office-based KTP and CO2 Laser Outcomes in Patients With Vocal Cord Lesions.

The purpose of this study is to test the outcomes of a CO2 laser device called AcuPulse Duo on vocal lesions and compare them to the most commonly used Aura KTP laser in order to determine which

  • 0 views
  • 04 Oct, 2022
  • 1 location
Deep Brain Stimulation for Severe Anorexia Nervosa (STIMARS)

such as obsessional compulsive disorder or pharmacoresistant epilepsy. Some case series reported promising results of DBS for severe and resistant AN. The aim of this study is to investigate the safety

  • 0 views
  • 04 Oct, 2022
  • 1 location
A Phase 1, Open-label Trial of AU-011 (Belzupacap Sarotalocan) to Determine the Feasibility and Safety of Intramural Injection With or Without Intratumoral Injection in Subjects With Non-muscle Invasive Bladder Cancer (NMIBC)

The main objectives of this study are i) to evaluate the incidence of AU-011 treatment-related adverse events, serious adverse events (SAEs) and dose-limiting toxicities (DLTs) and ii) to determine the feasibility of AU-011 treatment of non-muscle invasive bladder cancer utilizing intramural with or without intratumoral injection.

  • 0 views
  • 28 Oct, 2022
  • 2 locations
Fast Acute Sedation at Intensive Care vs. High-dose i.v. Anti-seizure Medication for Treatment of Non-convulsive Status Epilepticus (FAST-trial) (FAST)

This open-label, randomized multicenter trial aims at clarifying the standard of care of patients with non-convulsive status epilepticus not responding to treatment with benzodiazepines and at least one high-dose intra venous anti-seizure medication.

  • 0 views
  • 07 Oct, 2022
  • 1 location
In-depth Investigation of Brain Network Interactions (BNI)

Brain stimulation is a means to potentially remediate symptoms in a range of neurological and psychiatric diseases, however, precise targeting of stimulation is necessary to ensure efficacy. The proposed project will use recent advances in functional magnetic resonance imaging to delineate distributed brain networks within individuals, and use these network …

  • 128 views
  • 04 Oct, 2022
  • 1 location
Non-invasive Vagus Nerve Stimulation (nVNS) in Pediatric Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

This study will be conducted at Children's Healthcare of Atlanta, in Atlanta, Georgia for a total duration of 24 months. The electrical neuromuscular stimulation device used in this study is the VitalStim 400, which has been used in multiple previous clinical studies for modulation of pain and has received FDA …

immune globulin
plasma exchange
igiv
polyneuropathy
  • 0 views
  • 07 Oct, 2022
  • 1 location
'MindRest: Mindful Network Dynamics Regulation Under Stress (MindRest)

This study aims to assess the effectiveness of Mindfulness Based Stress reduction to reduce perceived stress in a highly stressed student population, while concurrently investigating neural mechanisms of the intervention. The investigators will perform a randomized, wait-list controlled trial assessing clinical and neurocognitive outcomes as well as measures of daily …

Accepts healthy volunteers
  • 0 views
  • 14 Oct, 2022
  • 1 location
XEN496 (Ezogabine) in Children With KCNQ2 Developmental and Epileptic Encephalopathy (EPIK)

To investigate the potential antiseizure effects of adjunctive XEN496 (ezogabine) compared with placebo in children with KCNQ2 Developmental and Epileptic Encephalopathy (KCNQ2-DEE).

tonic
seizure
electroencephalogram
ezogabine
ketogenic diet
  • 8 views
  • 04 Oct, 2022
  • 16 locations
A Randomized, Parallel-Group, Single-Attack, Open-Label Study to Evaluate the Efficacy of Diclofenac Potassium and Rimegepant for the Acute Treatment of Migraine (ATOM) (ATOM)

In a real-world population of adults with migraine, the investigators would like to investigate whether 50 mg diclofenac potassium is non-inferior to 75 mg rimegepant in terms of pain freedom at 2 hours after drug intake.

  • 0 views
  • 19 Oct, 2022
  • 1 location
A Randomized, Parallel-Group, Single-Attack, Open-Label Study to Evaluate the Efficacy of Almotriptan and Ubrogepant for the Acute Treatment of Migraine (ATOM). (ATOM)

In a real-world population of adults with migraine, the investigators would like to investigate whether 12.5 mg almotriptan is non-inferior to 50 mg ubrogepant in terms of pain freedom at 2 hours after drug intake.

  • 0 views
  • 10 Oct, 2022
  • 1 location