Scleroderma Clinical Trials

A listing of Scleroderma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 162 clinical trials
Deployment o the Multidisciplinary Prospective Cohort Imminent

Immune-mediated inflammatory diseases (IMIDs) most often affect young patients and have high impact on morbidity and mortality with a significant alteration in the quality of life of patients with professional, social and emotional repercussions. Beyond this burden, IMIDs share many common pathophysiological mechanisms and treatments, known as "targeted therapies". Despite …

disease or disorder
  • 0 views
  • 24 May, 2021
  • 1 location
Study to Assess Safety and Effectiveness of Branebrutinib Treatment in Participants With Active Systemic Lupus Erythematosus or Primary Sj gren's Syndrome or Branebrutinib Treatment Followed by Open-label Abatacept Treatment in Study Participants With Active Rheumatoid Arthritis

Syndrome (pSS), or branebrutinib treatment followed by open-label abatacept treatment in study participants with active Rheumatoid Arthritis (RA).

lupus
arthritis
abatacept
sjogren's syndrome
progressive systemic sclerosis
  • 328 views
  • 22 Sep, 2021
  • 1 location
Trial Comparing Irradiation Plus Long Term Adjuvant Androgen Deprivation With GnRH Antagonist Versus GnRH Agonist Plus Flare Protection in Patients With Very High Risk Localized or Locally Advanced Prostate Cancer

clinically significant cardiovascular events in the subgroup of patients at high risk of such events at baseline; documentation of side effects and quality of life, I-PSS and urinary tract

gonadotropin
ct scan
testosterone
androgen suppression
androgens
  • 135 views
  • 12 Sep, 2021
  • 42 locations
Autologous Stem Cell Transplantation for Progressive Systemic Sclerosis

Autologous stem cell therapy has been shown to be effective in patients with systemic sclerosis. Nevertheless treatment is associated with treatment related mortality and patients die during

diffuse cutaneous systemic sclerosis
fibrosis
cyclophosphamide
MRSS
pulmonary function test
  • 50 views
  • 26 Jan, 2021
  • 1 location
Brentuximab Vedotin for Systemic Sclerosis

There is significant unmet need for effective treatment options for Diffuse Cutaneous Systemic Sclerosis (dcSSc). The present study will be a dose-escalation safety trial of brentuximab vedotin

raynaud's syndrome
diffuse cutaneous systemic sclerosis
raynaud's phenomenon
MRSS
mycophenolate
  • 710 views
  • 18 Apr, 2021
  • 10 locations
Rehabilitation Program in Patients With Scleroderma

Scleroderma (or Systemic Sclerosis - SS) is one of the most neglected diseases worldwide, according to the World Health Organization. In the adult population with SS, the systemic effects of the

scleroderma
  • 0 views
  • 21 Sep, 2021
  • 1 location
Neutrophil Extracellular Traps in Systemic Sclerosis

Systemic sclerosis (SSC) is a systemic disease characterized by limited or diffuse cutaneous sclerosis, microangiopathy, overproduction of autoantibodies and variable organ damage due to

fibrosis
immune tolerance
microangiopathy
absolute neutrophil count
lupus
  • 79 views
  • 23 Jan, 2021
  • 1 location
Clinical Relevance of Thoracic Echography for the Early Diagnosis of Interstitial Lung Disease in Systemic Scleroderma - Pilot Study

Diffuse interstitial lung disease (PID) is the leading cause of death in systemic scleroderma (SSc). Major progress has recently been made in its therapeutic management. Early diagnosis is

interstitial lung disease
carbon monoxide
scleroderma
  • 0 views
  • 30 May, 2021
  • 1 location
High Dose Intravenous N-Acetylcysteine Versus Iloprost for Early Rapidly Progressive Diffuse Systemic Sclerosis

- Systemic sclerosis (scleroderma; SSc) is a rare, disfiguring systemic disorder characterized by fibrosis of the skin and visceral organs that alters every aspect of an

diffuse cutaneous systemic sclerosis
fibrosis
scleroderma
progressive systemic sclerosis
  • 33 views
  • 07 Nov, 2020
  • 4 locations
Feasibility and Preliminary Effects of the Resilience-based Energy Management to Enhance Wellbeing in Systemic Sclerosis (RENEW) Intervention

Researchers are testing a web-based peer-led program to help manage energy and symptoms in people who have scleroderma. Resilience-based, Energy Management to Enhance Wellbeing (RENEW) was

scleroderma
  • 0 views
  • 26 Jan, 2021
  • 1 location