Scleroderma Clinical Trials

A listing of Scleroderma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 174 clinical trials
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Functional Exercise Tests in Patients With Systemic Sclerosis

The aim of the study is to examine the validity of peripheral oxygen saturation measurement during the 6-minute walk test in patients with Systemic Sclerosis (SSc) and to examine the utility of

  • 0 views
  • 12 Sep, 2021
  • 1 location
None
Identifying Unique Pathogenic Macrophages in Systemic Sclerosis-ILD

Alveolar macrophages isolated from bronchoalveolar lavage (BAL) fluid from systemic sclerosis (SSc) patients with clinically significant lung fibrosis will be studied at baseline and at 6 months

fibrosis
progressive systemic sclerosis
bronchoscopy
rituximab
prednisone
  • 20 views
  • 28 Oct, 2021
  • 1 location
None
Endothelial Biomarkers of Systemic Sclerosis-associated Pulmonary Hypertension

Systemic sclerosis (SSc, AKA scleroderma) is an autoimmune condition characterized by endothelial damage and progressive fibrosis of the skin and internal organs. One of the leading causes of

systemic sclerosis
fibrosis
progressive systemic sclerosis
hypertension
autoimmune disease
  • 12 views
  • 16 Sep, 2021
  • 1 location
None
MPA AUC Monitoring in Patients Receiving MMF for Diffuse Cutaneous or Pulmonary Involvement in Systemic Sclerosis

cutaneous or interstitial lung damage of systemic sclerosis.

corticosteroids
cyclophosphamide
progressive systemic sclerosis
pulmonary involvement
immunosuppressive agents
  • 0 views
  • 28 Nov, 2021
  • 1 location
None
Evaluating Gut Imaging and Stool Biomarkers in Patients With Scleroderma-associated Gastrointestinal Disease

Systemic sclerosis (SSc) is characterized by autoimmunity and vasculopathy resulting in fibrosis of the skin and internal organs including the Gastrointestinal (GI) tract. Key unmet clinical

  • 0 views
  • 28 Jan, 2021
  • 5 locations
None
Volatile Organic Compounds (VOCs) as a Biomarker in Immune-mediated Pulmonary Arterial Hypertension (PAH)

hypothesize that at time of diagnosis the VOC profiles will discriminate patients with PAH-CTD and idiopathic PAH (IPAH) from patients with systemic sclerosis or systemic lupus erythematosus (CTD) without PAH

heart disease
connective tissue disease
hypertension
progressive systemic sclerosis
rheumatism
  • 1 views
  • 15 Sep, 2021
  • 1 location
None
Is a History of Pre-eclampsia a Risk Factor for Vascular Phenotype in Women With Systemic Sclerosis?

objective of the study: to determine if a history of pre-eclampsia before systemic sclerosis diagnosis is an independent risk factor for vascular phenotype in sclerodermic women. Secondary objective

  • 0 views
  • 28 Jan, 2021
  • 10 locations
None
Connective Tissue Diseases and Lung Manifestations

Despite a number of prospective studies already initiated in the past years, the current epidemiology and course of interstitial lung disease (ILD) and pulmonary hypertension (PH) in patients with connective tissue disease (CTD) is still not well defined, particularly regarding its prevalence, incidence and the management of a broad spectrum …

rheumatism
pulmonary hypertension
diagnostic procedures
interstitial lung disease
spirometry
  • 0 views
  • 24 Jan, 2021
  • 1 location
None
Meir Medical Center Rheumatologic Biobank

Serum, synovial fluid and skin biopsies from patients will be collected to the biobank with rheumatoid diseases. These samples will later be used for clinical and basic research, following approval of each specific study by the IRB. The investigators intend to extract protein, DNA and RNA from each sample.

  • 0 views
  • 22 Jan, 2021
  • 1 location
None
The Influence of Extracorporeal Photopheresis on Skin Sclerosis

extended to the treatment of Graft-versus-Host Disease (GvHD), systemic sclerosis, and in the field of solid organ transplantation. There is also evidence supporting the use of ECP in generalized morphea

  • 0 views
  • 21 Feb, 2021
  • 1 location