Scleroderma Clinical Trials

A listing of Scleroderma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 155 clinical trials
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A phase 3, randomized, placebo-controlled study to assess the efficacy and safety of an investigational medication versus placebo in patients with systemic sclerosis

A phase 3, randomized, placebo-controlled study to assess the efficacy and safety of an investigational medication versus placebo in patients with systemic sclerosis

  • 1104 views
  • 23 Nov, 2020
  • 1 location
featured
A Study of RDC-1036 (ALKS 37) in Adults With Opioid-induced Constipation

A Study of RDC-1036 (ALKS 37) in Adults With Opioid-induced Constipation

  • 94 views
  • 08 Nov, 2020
  • 1 location
featured
A 12-month, Randomized, Rater- and Dose-blinded Study to Compare the Efficacy and Safety of Fingolimod 0.25 mg and 0.5 mg Administered Orally Once Daily With Glatiramer Acetate 20 mg Administered Subcutaneously Once Daily in Patients With Relapsing-remitting Multiple Sclerosis

A 12-month, Randomized, Rater- and Dose-blinded Study to Compare the Efficacy and Safety of Fingolimod 0.25 mg and 0.5 mg Administered Orally Once Daily With Glatiramer Acetate 20 mg Administered Subcutaneously Once Daily in Patients With Relapsing-remitting Multiple Sclerosis

  • 74 views
  • 25 Mar, 2021
  • 1 location
A Comparison of Intra-operative Radiotherapy Boost With External Beam Radiotherapy Boost in Early Breast Cancer.

TARGIT-Boost is an international randomised clinical trial designed to test the hypothesis that the tumour bed boost delivered as a single dose of targeted intraoperative radiotherapy (TARGIT-B) is superior to the conventional course of external beam radiotherapy boost (EBRT-Boost), especially in women with high risk of local recurrence. It is …

  • 289 views
  • 22 Jan, 2021
  • 42 locations
Platelet Gel in Systemic Sclerosis

- Systemic sclerosis (scleroderma; SSc) is a connective tissue disease characterized by a progressive fibrosis of the skin and visceral organs. - A diffuse cutaneous

transforming growth factor beta-1
growth factor
progressive systemic sclerosis
prostanoids
prostacyclin
  • 24 views
  • 07 Nov, 2020
  • 1 location
Low-Dose Oral Imatinib for Scleroderma Pulmonary Involvement

The purpose of this study is to verify effect and tolerability of imatinib on pulmonary and skin fibrosis in patients affected by systemic sclerosis.

pulmonary function test
imatinib
immunosuppressive agents
alveolitis
progressive systemic sclerosis
  • 33 views
  • 07 Nov, 2020
  • 1 location
Effect of the Use of Specific Oral Hygiene Devices on Gingival Health Among Patients With Systemic Sclerosis

Systemic sclerosis is a rare multisystem connective-tissue disorder characterized by three major pathological hallmarks: widespread fibrosis, vasculopathy and immunological abnormalities. This

vascular disease
fibrosis
  • 0 views
  • 25 Jul, 2021
  • 1 location
iCareDx PSS-1 Point-of-Care (POC) Assay for Detection of COVID-19

Purpose of this clinical investigation is to establish the performance of the iCareDx PSS-1 RT PCR POC Testing Platform which is used to detect COVID-19 in symptomatic patients using the

  • 0 views
  • 30 Jun, 2021
  • 1 location
The Effectiveness and Safety of FK-506 for the Treatment of Posner-Schlossman Syndrome

To evaluate the effectiveness and safety of tacrolimus eye drops (FK-506) in the treatment of Posner-Schlossman Syndrome. It is expected to collect 30 patients with PSS who are in the

  • 0 views
  • 03 May, 2021
  • 1 location
Effect of Vibroacoustic Therapy on Acute Stress in University Students

), galvanic skin response (GSR), salivary cortisol, standardized psychological questionnaires - visual analogue scales for stress (VAS-stress) and Perceived Stress Scales-10, Czech version (PSS-10). It is

  • 0 views
  • 15 Jun, 2021
  • 1 location