Schizophrenia and Schizoaffective Disorders Clinical Trials

A listing of Schizophrenia and Schizoaffective Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 246 clinical trials
This Study Tests Whether BI 425809 Together With Brain Training Using a Computer Improves Mental Functioning in Patients With Schizophrenia

This is a study in adults with schizophrenia. The study tests whether a medicine called BI 425809 together with brain training improves mental abilities. Participants take study medication once a day for 12 weeks. At the start of the study, the participants are put into 2 groups. It is decided …

anticholinergics
cognitive training
antipsychotics
antidepressants
clozapine
  • 773 views
  • 18 Sep, 2021
  • 60 locations
A Clinical Study to Evaluate the Long-term Safety and Tolerability of an Investigational Drug in People With Schizophrenia

This is a clinical trial to determine the long-term safety and tolerability of an investigational drug in people with schizophrenia. Participants in the study will receive the drug being studied. This study is accepting male and female participants between 13 and 65 years old who have been diagnosed with schizophrenia …

  • 44 views
  • 27 Jan, 2021
  • 74 locations
A Clinical Trial That Will Study the Efficacy and Safety of an Investigational Drug in Acutely Psychotic People With Schizophrenia

A clinical trial to study the efficacy and safety of an investigational drug in acutely psychotic people with schizophrenia. Participants in the study will either receive the drug being studied or a placebo. This study is accepting male and female participants between 18 -65 years old who have been diagnosed …

psychosis
hallucinations
psychotic symptoms
delusions
  • 65 views
  • 25 Jan, 2021
  • 39 locations
A Study to Evaluate the Safety and Efficacy of BIIB104 in Participants With Cognitive Impairment Associated With Schizophrenia (CIAS)

The primary objective of the study is to evaluate the efficacy of BIIB104 in participants with CIAS, using the Working Memory Domain of the MATRICS Consensus Cognitive Battery (MCCB). The secondary objectives of this study are to evaluate the safety and tolerability of BIIB104 in participants with CIAS, and to …

delusions
cognitive impairment
psychiatric treatment
antipsychotics
clozapine
  • 265 views
  • 09 Sep, 2021
  • 103 locations
Using Digital Media Advertising to Reduce the Duration of Untreated Psychosis

There is compelling evidence that longer duration of untreated psychosis independently predicts negative outcomes. The proposal aims to explore whether targeted and proactive online outreach through search engine advertisements, coupled with engaging, informative, and interactive online resources, can effectively reduce the duration of untreated psychosis and facilitate earlier treatment initiation …

psychosis
  • 0 views
  • 30 Apr, 2021
  • 2 locations
A Study of the Long-term Safety and Tolerability of an Investigational Drug in People With Schizophrenia.

A clinical study to evaluate the long-term safety and tolerability of an investigational drug in people with schizophrenia. This study is accepting male and female participants between 18 years old -65 years old who have been diagnosed with schizophrenia. This study will be conducted in approximately 50 study centers worldwide. …

antipsychotics
quetiapine
scid
  • 100 views
  • 19 Aug, 2021
  • 46 locations
Extension Study of Pimavanserin for the Adjunctive Treatment of Schizophrenia

To evaluate the long-term safety and tolerability of pimavanserin after 52 weeks of adjunctive treatment in subjects with schizophrenia

aripiprazole
cariprazine
olanzapine
adjunctive treatment
brexpiprazole
  • 254 views
  • 29 Jan, 2021
  • 152 locations
Trial to Investigate the Safety and Efficacy of GWP42003-P Versus Placebo as Adjunctive Therapy in Participants With Schizophrenia Experiencing Inadequate Response to Ongoing Antipsychotic Treatment

This study will be conducted to evaluate the efficacy, safety, and tolerability of GWP42003-P versus placebo in participants with schizophrenia experiencing inadequate response to ongoing antipsychotic treatment.

psychosis
psychotic symptoms
olanzapine
antidepressants
psychiatric disorder
  • 7 views
  • 05 Sep, 2021
  • 79 locations
Efficacy and Safety of Pimavanserin as Adjunctive Treatment for the Negative Symptoms of Schizophrenia

To evaluate the efficacy and safety of adjunctive pimavanserin compared with adjunctive placebo in the treatment of negative symptoms of schizophrenia

aripiprazole
cariprazine
olanzapine
adjunctive treatment
risperidone
  • 5 views
  • 31 Jul, 2021
  • 76 locations
Efficacy and Safety of MK-8189 in Participants With an Acute Episode of Schizophrenia (MK-8189-008)

The purpose of this study is to evaluate the efficacy and safety of MK-8189 at a range of doses (8 mg, 16 mg, and 24 mg once daily) in adult participants who have an acute episode of schizophrenia according to Diagnostic and Statistical Manual of Mental Disorders 5th Edition (DSM-5) …

risperidone
  • 0 views
  • 23 Sep, 2021
  • 66 locations