Sarcoma Clinical Trials

A listing of Sarcoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 653 clinical trials
Interest of Peri Operative CHemotherapy In Patients With CINSARC High-risk Localized Soft Tissue Sarcoma (CHIC-STS01)

survival as compared with standard management in patients with resectable STS, considered as high-risk according to CINSARC (Complexity Index in SARComas) signature. After signed informed consent

soft tissue sarcoma
dacarbazine
ifosfamide
metastasis
platelet count
  • 0 views
  • 11 May, 2022
  • 20 locations
Phase III Trial of Anlotinib, Catequentinib in Advanced Alveolar Soft Part Sarcoma, Leiomyosarcoma, Synovial Sarcoma (APROMISS) (APROMISS)

THIS STUDY IS CURRENTLY RECRUITING PATIENTS WITH ALVEOLAR SOFT PART SARCOMA ONLY AND IS NO LONGER RECRUITING PATIENTS WITH SYNOVIAL SARCOMA OR LEIOMYOSARCOMA.

alveolar soft part sarcoma
synovial sarcoma
leiomyosarcoma
measurable disease
ejection fraction
  • 334 views
  • 27 Jan, 2022
  • 22 locations
RNASARC - Molecular Screening Program of Soft Tissue Sarcomas With Complex Genomic Profile to Detect NTRK1/2/3, ROS1 or ALK Gene Fusions. (RNASARC)

This trial is a multicenter, prospective cohort study aiming to describe molecular profiles of soft tissue sarcoma (STS) with complex genomic profiles in particular to assess the incidence of

soft tissue sarcoma
x-rays
liposarcoma
malignant peripheral nerve sheath tumor
angiosarcoma
  • 40 views
  • 27 Feb, 2022
  • 10 locations
A Study Comparing the Efficacy of L19TNF+Doxorubicin vs Doxorubicin Alone as First-line Therapy in Patients With Advanced or Metastatic Soft Tissue Sarcoma (FIBROSARC)

metastatic soft-tissue sarcoma patients. In the study, 102 patients will be randomized in a 1:1 ratio to receive doxorubicin treatment (Arm 1) or L19TNF treatment in combination with doxorubicin (Arm

malignant peripheral nerve sheath tumor
metastatic soft tissue sarcoma
alveolar soft part sarcoma
epithelioid sarcoma
synovial sarcoma
  • 0 views
  • 21 Apr, 2022
  • 9 locations
Surgery With Our Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcoma

This is a multicenter, randomized, open label phase lll trial to assess whether preoperative chemotherapy, as an adjunct to curative-intent surgery, improves the prognosis of high risk DDLPS (dedifferentiated Liposarcoma) and LMS (Leiomyosarcoma) patients as measured by disease free survival. After confirmation of eligibility criteria, patients will be randomized to …

cancer
liposarcoma
gilbert's syndrome
neutrophil count
systemic therapy
  • 0 views
  • 30 Jul, 2021
  • 23 locations
A Randomized, Open-Label Phase 1/2 Study Evaluating Ramucirumab in Pediatric Patients and Young Adults With Relapsed, Recurrent, or Refractory Desmoplastic Small Round Cell Tumor

This study is being conducted to test the safety and efficacy of ramucirumab in combination with other chemotherapy in the treatment of relapsed, recurrent, or refractory desmoplastic small round cell tumor (DSRCT) in children and young adults. This trial is part of the CAMPFIRE master protocol which is a platform …

cancer
neutrophil count
desmoplastic
vinorelbine
measurable disease
  • 4 views
  • 17 Sep, 2022
  • 55 locations
A Phase 1 Study of LY3410738 Administered to Patients With Advanced Solid Tumors With IDH1 or IDH2 Mutations

This is an open-label, multicenter Phase 1 study to evaluate safety, tolerability and preliminary efficacy of oral LY3410738 in patients with isocitrate dehydrogenase 1 (IDH1) arginine 132 (R132)-mutant advanced solid tumors, including but not limited to cholangiocarcinoma, chondrosarcoma, and glioma or isocitrate dehydrogenase 2 (IDH2) arginine 140 (R140) or arginine …

systemic therapy
gemcitabine
drainage
metastasis
measurable disease
  • 14 views
  • 19 Aug, 2022
  • 35 locations
Development of Clinical and Biological Database (BCBInstitut)

The BCB is a tool: for research in analytical and public health epidemiology, biological research and for the development of data useful for clinical research and therapeutic trials; to help scientists understand and explain phenomena ranging from the interaction of molecules to the whole metabolism of the organism in normal …

cancer
gastrointestinal cancer
breast cancer
sarcoma
anal canal
  • 4 views
  • 27 Feb, 2022
  • 1 location
A Study of Oral LOXO-292 (Selpercatinib) in Pediatric Participants With Advanced Solid or Primary Central Nervous System (CNS) Tumors (LIBRETTO-121)

This is an open-label, multi-center Phase 1/2 study of oral LOXO-292 in pediatric participants with an activating rearranged during transfection (RET) alteration and an advanced solid or primary CNS tumor.

metastasis
measurable disease
kidney function tests
RET
cns tumor
  • 38 views
  • 20 Jul, 2022
  • 19 locations
Biological Characterisation of High Risk CHildhood Cancer in Children, Adolescents and Young Adults (MICCHADO) (MICCHADO)

Methodology Prospective, multicentric, open, non-randomised, non-therapeutic, interventional study

histological diagnosis
metastatic neuroblastoma
myeloid leukemia
sarcoma
kidney tumors
  • 30 views
  • 16 Mar, 2022
  • 13 locations