Sarcoma Clinical Trials

A listing of Sarcoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 240 clinical trials
Safety and Effectiveness of Quizartinib in Children and Young Adults With Acute Myeloid Leukemia (AML), a Cancer of the Blood

Quizartinib is an experimental drug. It is not approved for regular use. It can only be used in medical research. Children or young adults with a certain kind of blood cancer (FLT3-ITD AML) might be able to join this study if it has come back after remission or is not …

cancer
fludarabine
cytarabine
methotrexate
consolidation therapy
  • 51 views
  • 15 Jul, 2022
  • 39 locations
Exercise and Soft Tissue Sarcoma

patients with a primary diagnosis of soft tissue sarcoma undergoing treatment with neoadjuvant radiation therapy and surgical resection. Patients with upper or lower extremity sarcomas will be considered

immunomodulators
soft tissue sarcoma
  • 0 views
  • 22 Apr, 2022
  • 1 location
Targeting ATR in Soft-tissue Sarcomas (TARSARC)

Multicenter, prospective, open-labeled, 2-arm, non-comparative randomized phase II trial to assess the antitumor activity of berzosertib in association with gemcitabine

  • 0 views
  • 08 Aug, 2022
  • 1 location
Trabectedin Plus Radiotherapy in Soft Tissue Sarcoma Patients (TRASTS)

unresectable or not oncologically recommended metastasectomy of limited to lung metastases soft tissue sarcoma. Cohort B: Patients with locally advanced resectable Myxoid Liposarcoma. Cohort C: Patients

malignant fibrous histiocytoma
soft tissue sarcoma
angiosarcoma
leiomyosarcoma
measurable disease
  • 25 views
  • 17 Jun, 2022
  • 13 locations
Treatment of Metastatic Soft Tissue Sarcoma (STS) Patients (FIBROSARC USA) (FIBROSARC US)

The present study is an open-label, randomized, controlled, two-arm multi-center study of the efficacy of L19TNF treatment in combination with doxorubicin versus doxorubicin alone in metastatic leiomyosarcoma patients.

alveolar soft part sarcoma
soft tissue sarcoma
angiosarcoma
leiomyosarcoma
measurable disease
  • 0 views
  • 06 May, 2022
  • 8 locations
Surufatinib in Patients With Osteosarcoma and Soft Tissue Sarcoma

The purpose is to evaluate the effectiveness and safety of Surufatinib in patients with osteosarcoma and soft tissue sarcoma after Standard chemotherapy therapy.

  • 0 views
  • 13 May, 2022
  • 1 location
Hypofractionated vs Conventional Fractionated RT in Soft Tissue Sarcomas

This research study is designed to find out if radiation therapy treatment prior to surgery is safe and effective to treat soft tissue sarcomas. 30 participants with soft tissue sarcoma will be

neutrophil count
kidney function tests
soft tissue sarcoma
sarcoma of the extremity
  • 0 views
  • 27 May, 2022
  • 1 location
FAZA PET/MRI Sarcoma

will be used to measure hypoxia in sarcoma tissues and will occur for: Arm A: before neo-adjuvant radiation/chemotherapy treatment Arm B: before surgery (optional). After the FAZA PET/MRI

cancer chemotherapy
synovial sarcoma
immunomodulators
undifferentiated pleomorphic sarcoma
leiomyosarcoma
  • 17 views
  • 19 Apr, 2022
  • 1 location
Abemaciclib for Bone and Soft Tissue Sarcoma With Cyclin-Dependent Kinase (CDK) Pathway Alteration

This is a single-arm, phase II study that will enroll a total of 45 subjects. All subjects will have a confirmed diagnosis of metastatic or unresectable soft tissue sarcoma or bone sarcoma. All

renal function
soft tissue sarcoma
metastasis
neutrophil count
measurable disease
  • 11 views
  • 23 Apr, 2022
  • 4 locations
Nivolumab and BO-112 Before Surgery for the Treatment of Resectable Soft Tissue Sarcoma

This phase I trial studies the side effects of BO-112 when given together with nivolumab before surgery in treating patients with soft tissue sarcoma that can be removed by surgery (resectable

cancer
synovial sarcoma
tumor cells
soft tissue sarcoma
leiomyosarcoma
  • 0 views
  • 13 May, 2022
  • 1 location